 | |
| BIOC0210-4 | Functional properties of biological macromolecules
 |
|
| Duration : | 30h Th, 20h Pr, 15h Mon. WS |
|
| Credits/ECTS : |
|
|
| Holder(s) : | Edwin De Pauw, André Matagne |
|
| Language : | French language |
|
| Course contents : | Partim Physical-chemistry: Chapter 1: Molecular weight, primary structure, topology. Chapter 2: The chemical potential. Chapter 3: Biomolecules in electrical fields. Chapter 4: Microscopic aspects of chemical kinetics.
Partim Enzymology: Chapter 1: General properties of enzymes. Chapter 2: Steady-state kinetics. Chapter 3: Enzyme inhibition. Chapter 4: Effect of pH, temperature, viscosity and other experimental factors. Chapter 5: Reactions of two substrates. Chapter 6: Transient-state kinetics. Chapter 7: Cooperativity and allosteric interactions. Chapter 8: Enzyme inactivators. Chapter 9: Enzyme cofactors. Chapter 10: Mechanism of chymotrypsin. Chapter 11: Basic catalytic principles. Chapter 12: Regulation of catalytic activity. |
|
| Course objective : | Partim Physical Chemistry. The objective of this curse is to introduce basic concepts underlying the properties of biopolymers.
Partim Enzymology. The aim of the course is to make students familiar with enzyme mechanisms and understand enzyme kinetics. |
|
| Prerequisites : | Partim Physical Chemistry. Prerequisites: The chemistry courses (BAC1 and BAC2) and the course "Chemistry of biological macromolecules" (BAC3)
Partim Enzymology. Course on "Chemistry of biological macromolecules" (BAC3 Biology), which includes an introduction to enzyme catalysis (chapters 1-3). |
|
| Workshops : | Problems tutorials and introduction to the scientific instruments |
|
| Organization : | 30 hours of lectures, given with the help of a few transparencies, blackboard and white chalk |
|
| Written notes : | Lecture notes will be available following the lectures |
|
| Assessment : | A written exam will be organized for each part of the course and it will be compulsory to obtain at least 8/20 for each of them. |
|
| Contacts : | Partim Physical Chemistry. Edwin De Pauw, Professeur Ordinaire, Laboratoire de spectrométrie de masse, CART/GIGA-R Institut de Chimie B6c, bureau R, Allée de la Chimie, 3, Université de Liège, B4000 Liège (Sart-Tilman), Tel.: +32 (0)4 3663415, Fax: +32(0)4 3663413, Email: e.depauw@ulg.ac.be(amatagne@ulg.ac.be http://www.mslab.ulg.ac.be
)
Partim Enzymology. Professor André Matagne, PhD, Enzymology and Protein Folding, Centre for Protein Engineering, Life Sciences Department, Institut de Chimie B6c (room 3/1), Allée de la Chimie, 3, University of Liège, B4000 Liège (Sart-Tilman), Tel.: +32 (0)4 3663419, Fax: +32 (0)4 3663396, Email: amatagne@ulg.ac.be, http://www.cip.ulg.ac.be/amatagne.htm (http://www.cip.ulg.ac.be/amatagne.htm" target=_blank eudora="autourl) |
|
|
| |
