University of Liege | Version française
Study programmes 2009-2010Last update : 28/06/2010
VETE0052-1  Pharmacotherapy and toxicology of domestic animals I and II
Duration :  25h PCL
Credits/ECTS :  
Master in Veterinary Medicine, 2nd year1
Holder(s) :  Pascal Gustin
Language :  Langue française
Course contents :  In the course VETE0379-1, the properties of the different classes of pharmacologic substances are reviewed systematically. In GMV2, students learn therapeutics in a case-based multidisciplinary approach.
Course objective :  To learn how to make a rational therapeutic choice in a scientific, clinical and legal context. Students are trained to make decisions in real and complex situations, making use of the different disciplines.

Decision making is complex in veterinary medicine. Therefore it is essential to develop and implement teaching tools to train students and practitioners to make more informed decisions, based on scientific evidence. This module will include PBL (problem based learning) sessions to answer to a clinical question about therapeutics. It will integrate the Evidence Based Medicine approach.

Evidence-based medicine is the conscientious, explicit and judicious use of current best evidence in making decisions about the care of individual patients (animals). Good veterinarians and health professionals use both individual clinical expertise and the best available external evidence, and neither alone is enough. Without clinical expertise, practice risks becoming tyrannised by evidence. Even excellent external evidence may be inapplicable to or inappropriate for an individual patient. Without current best evidence, practice risks becoming rapidly out of date, to the detriment of animals. Evidence-based medicine involves tracking down the best external evidence with which to answer our clinical questions.

At the end of the module, learners should be able to :



  • Give a definition of EBM and list its objectives,
  • List and explain the steps of EBM,
  • Explain how to search the literature,
  • Sort out papers by scientific strength of evidence,
  • Know the principles of cursory reading of the literature (reading by "layers")
  • Understand and explain what is a bias and a random error,
  • Identify the future applications of EBM in their practice,
  • Integrate EBM in the process of decision making


In addition, learners should be able to



  • Understand the different components of decision making and integrate them in a multidisciplinary context,
  • Give a list of questions for each of the components of decision making in common problems that are encountered in practice,
  • Identify the relevant scientific information to answer to the foreground and the background questions that have been raised,
  • Link the different disciplines that are concerned by the problem,
  • Evaluate the internal validity of scientific papers,
  • Evaluate the external validity of the scientific information (is it applicable to the case, can it be generalized?)
  • Write a technical sheet about a therapeutic intervention,
  • Synthesize the elements and justify their decisions,
  • Communicate their findings to their peers,
  • Evaluate others and themselves,
  • Work in a team,
  • Write a report
Prerequisites :  Therapeutics is based on knowledge that was gained in other courses. However it is a discipline in itself that must be taught in a multidisciplinary context that integrates fundamental and paraclinical disciplines.
Organization :  First Tuesday : Information session (2 hours).

Week 1 :

  • Introduction to EBM (Monday)
The educational intervention is a 2 hour short course. It is interactive. The teacher will ask the participation of the audience during the power point presentation. The examples will refer to questions about therapeutics, applied to different species. For example, EBM could be applied to questions about treatment of bovine respiratory disease or psoroptic mange. Real cases will be used to reflect about therapeutic options and decisions. The template of the course will remain the same throughout the year but problems and examples will change. This aims to standardize the course and allows for its educational evaluation and regulation.

The short course begins with a pre-test (Multiple choice questions) to assess student's background. It ends with a post-test and immediate feed-back is given. These tests are also used to present the objectives of the course and stimulate auto-evaluation.



  • Seminar of therapeutics
A therapeutical problem or question is presented and discussed with the group. The aim is to integrate pharmacologic knowledges in a multidisciplinary context, that leads to a more informed therapeutic decision.

  • Self-learning
A multimedia room is available with several computers for self-learning. Students work by themselves on common problems encountered in practice.





Week 2 :



Students will work in teams to solve problems with a multidisciplinary approach. The module is detailed on the website of the department.
Written notes :  
  • Short course : Module d'introduction à la pratique de l'Evidence Based-Medicine (EBM) pour prendre une « décision médicale mieux informée » (DMMI) », Jean-Michel Vandeweerd.
  • Manuel du module multidisciplinair
  • Personnal search of the literature
Assessment :  Final examination : oral presentation of an individual work about the therapeutic strategy on a clinical case



Students will be exempted if they have obtained a grade > 9 for their team work in the multidisciplinary module. The assessment of this work will entails an auto-evaluation of students, a peer evaluation, and an assessment by the promoter of the subject of the PBL and the tutor. The criteria for assessment will include :



  • Knowledge of the pharmacological background
  • Approach by the group to solve the problem
  • Quality of the review of the literature, its evaluation and the best evidence used to make a decision
  • Ability to argue a therapeutic choice
  • Quality of oral presentation and argumentation
If the mark for the group work is insufficient, the team will have the possibility to submit a written work that should take into account the feed-back given by the assessors. The final grade (that will allow for exemption of a final examination if it is > 9 ) will then be administered.



A detailed explanation of the course, of its objectives, and of the different tasks, can be consulted on the website of the department (for Erasmus Out students also)

http://www.fmv-dsfo.ulg.ac.be/pharmaco/messages.php



The module is compulsory. If the absence is not justified, there will be a sanction and the grade will be changed accordingly. Students should be in time at the course. A delay of more than 15 minutes will be considered as an absence. All documents that justify the absence should be submitted to the department the day that follows the absence.
Contacts :  P. Gustin,
E-mail : p.gustin@ulg.ac.be
Tél. : 04/ 366 41 75


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