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| INFO0430-1 | Notions of bioinformatics | |||||
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| Duration : | 10h Th | |||||
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| Holder(s) : | N... | |||||
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| Substitute(s) : | Olivier Peulen | |||||
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| Course contents : | The course will define and describe stakes of bioinformatics in XXIst century. Genomic and proteomic databases will be described. Retrieving of sequences in databases will be explained. Some algorithms of exon detection will be exposed. Notions of distance, similarity and homology will be introduced. Dot plots, alignment methods, consensus sequence detection and PCR primer design will be introduced. Content : - Introduction and scenario - Informatic tool - Cell constituants and bioinformatics - Databases - Nucleic acids - Proteins - Others - Sequence retrieval - Difficulties of sequence analysis - Exon detection - Internal signals-based - Nucleotide composition-based - Distance, similarity and homology : what do they mean ? - Sequence comparison and analysis - Dot-plots - Sequence alignment - Consensus detection - Other tools | |||||
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| Course objective : | Students might be able to use basic bioinformatic softwares available on WWW and to understand mechanisms involved in this softwares. This understanding might allow them to determine limitations of each procedure. | |||||
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| Prerequisites : | Basic knowledge of web. | |||||
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| Workshops : | Néant | |||||
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| Organization : | Le cours sera donné au semestre 1 de la licence à raison de 2 heures par semaine pendant 5 semaines. Le cours débute le mardi 19/10 à 10H30 dans le local D50 du CHU. | |||||
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| Written notes : | Syllabus (~100 pages) and a CD with powerpoint files are available. Syllabus can be obtained at Intercopy or on My ULg website. Powerpoint files can be obtained on My ULg website. | |||||
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| Assessment : | Oral examination | |||||
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| Contacts : | Olivier Peulen Biochimie et Physiologie Générale Institut de Chimie B6C Tél: 04/366.35.75 E-mail: Olivier.Peulen@ulg.ac.be | |||||
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| Remarks : | Textbook : Introduction to Bioinformatics, Arthur M. Lesk, Oxford University Press (2002) | |||||
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ULg : Students and Studies Administration - Academic Affairs
Contact : Monique Marcourt, direction A.E.E.
Date of data : 27/02/2006
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