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| CHIM0255-1 | Structure and dynamics of biological macromolecules, section : structure, section : dynamics | |||||
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| Duration : | 40h Th, 40h Pr | |||||
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| Holder(s) : | Paulette Charlier, Pierre Colson, Gabriel Llabres, André Matagne | |||||
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| Course contents : | Dynamics part (20h + 20h) The lecture begins with a short review of the spectral transitions. Afterwards, the following spectroscopic techniques are studied in detail : uv-visible absorption, linear and circular dichroïsms, fluorescence and its polarisation, I.R. spectroscopy and surface plasmonic resonance. For each technqiue, experimental aspects and applications to the study of protein and nucleic acid conformations and of their interactions with small ligands will be developed | |||||
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| Course objective : | Dynamics part (20h + 20h) Increase the qualifications of the student concerning the spectroscopic methods available for the study of the conformational dynamics of proteins (folding and unfolding), nucleic acids and their interactions. | |||||
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| Prerequisites : | Dynamics part : Chemistry of Biological Macromolecules (1st Licence in Biochemistry) Functional properties of biological macromolecules (1st Licence in Biochemistry | |||||
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| Organization : | Dynamics part : This lecture will be given as a classical form (as interactive as possible) by the two teachers according to their specific qualifications | |||||
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| Written notes : | Dynamics part : Lecture notes will be available. Reference books : - Biophysical Chemistry, Cantor and Schimmel - Intrduction to protein chemistry, Branden and Tooze - Principles of Physical Chemistry, Van Holde et al. - Biological Spectroscopy, Campbell and Dwek -Physical Biochemistry, Sheehan | |||||
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| Assessment : | Dynamics part: written examination | |||||
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| Contacts : | Dynamics part : Pierre Colson, Chargé de Cours Office : 3/73B, Chemistry Institute (B6c), Sart-Tilman, 4000 - Liège 1 , Belgium Call : 00 32 (0)4/3663406 Fax : 00 .2 (0)4/3664577 e-mail : P.Colson@ulg.ac.be André Matagne, Chercheur Qualifié FNRS - Institut de Chimie, Sart-Tilman (B6c) - Bureau 3/7B Call : 00 32 (0)4/366.34.19 - Sec : 00 32 (0)4/366.33.41 Fax : 00 32 (0)4/366.33.64 e-mail : amatagne@ulg.ac.be | |||||
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ULg : Students and Studies Administration - Academic Affairs
Contact : Monique Marcourt, direction A.E.E.
Date of data : 27/02/2006
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