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| BIOL0113-1

 | Biologie générale préparatoire aux sciences biomédicales et dentaires, y compris l'introduction à la biologie moléculaire et à l'anatomie humaine, l'embryologie générale et la génétique générale - General biology preparing to biomedical and dental sciences, including introduction to molecular biology - General Embryology - General Genetics - Introduction to Human Anatomy

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| Duration : | General biology preparing to biomedical and dental sciences, including introduction to molecular biology : 65h Th, 40h Pr, 30h QA Sess. General Embryology : 10h Th General Genetics : 10h Th Introduction to Human Anatomy : 30h Th, 20h QA Sess.
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| Credits/ECTS : |
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| Holder(s) : | General biology preparing to biomedical and dental sciences, including introduction to molecular biology : Vincenzo Castronovo
General Embryology : Jean‑Pierre Schaaps
General Genetics : Vincent Bours
Introduction to Human Anatomy : Pierre Bonnet
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| Course contents :
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 |  | General biology preparing to biomedical and dental sciences, including introduction to molecular biology |

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 | - Life molecules (6 hours) - The cell (3 hours) - Animal anatomy and physiology (6 hours) - Cellular energy metabolism (4 hours) - DNA, genes and chromosomes (3 hours) - From genes to proteins (3 hours) - Cell cycle, mitosis, meiosis and cell death (6 hours) - Introduction to molecular biology (3 hours) - From the origins of life to biodiversity (2 hours) - Prokaryotes (2 hours) - Protists (2 hours) - Mycetes (2 hours) - From unicellular to pluricellular organisms: advantages and drawbacks of pluricellularity (3 hours) - The kingdom of plants (6 hours) - The diversity of the animal kingdom (8 hours) - Introduction to the evolution of living organisms (4 hours) - Ecology basics and geobiochemical cycles (4 hours) |
 |  | General Embryology |

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 | How can a living being develop from a single cell? How do incredibly precise steps follow each other in space and time to form a photoreceptor organ, a lens and muscles able to properly control its sequence as well as structures secreting the fluid for the transmission of light? Where will the left and the right sides, the belly and the back, the head and the tail appear from an apparently unorganized cell mass? Whether cells are free or structured into tissues, they get organized, move and evolve in terms of shape and function following a single rule: close interdependence. Nature needed more than 2 billion years to create what we see today not by developing endless basic information items (we have only 30,000 genes) but by increasing the number of possible multiple regulations (if there was a coding gene for each iris structure, there would not be enough of them!). The General Embryology course aims at explaining the different steps and above all the mechanisms used for building autonomous organisms. |
 |  | General Genetics |

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 | The course is intended for 1st-year students in medicine and dental sciences. It aims at introducing basic genetic concepts while demonstrating prospects in the medical and biological fields. The course presents theoretical bases and describes the human genome, as well as simple and complex genes transmission. It also deals with the essentials of population genetics and focuses on the issue of genetic defects and medical consequences.
Chapter 1. Genes and genome Chapter 2. Gene transmission Chapter 3. Complex gene transmission Chapter 4. Population genetics Chapter 5. Genetic defects |
 |  | Introduction to Human Anatomy |

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 | Introduction
Historical overview - Definition of Anatomy
General considerations
Anatomical studies: dissection, microscopic study, use of informations from medical imaging, use of computer assisted imaging, anatomical tools for description
Sytematic anatomy
-locomotor system -cardiovascular system -respiratory system -digestive system -nervous system -uro-genital and reproductive systems
Introduction to topographic and clinical anatomy |
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| Course objective :
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 |  | General biology preparing to biomedical and dental sciences, including introduction to molecular biology |

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 | The Cell, Organism and Population Biology course (Evolution, Diversity and Ecology) plays a central role in the education of biomedical sciences students. It presents the fundamental concepts ruling living matter and is a real journey into the world of the living. Starting from the smallest particles, we will see how they organize into increasingly complex structures, which acquire new properties and simultaneously account for the uniqueness and extreme diversity of living matter. We will dwell on lifes basic element: the cell. We will focus on the way in which it learnt to use vital energy and on the mechanism through which it reproduces itself from generation to generation while retaining its own specific characteristics. We will then deal with multicellular organisms from the simplest to the most complex specimens and identify how they gradually adapted to environmental constraints. Ecology basics will allow us to more precisely define Mans impact on living organisms. |
 |  | General Embryology |

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 | Session 1:
- The development of gametes: general principles - Oogenesis - Spermatogenesis
Session 2:
- Fertilization - Segmentation
Session 3:
- Didermic embryos and development of placenta and amniotic membranes - Gastrulation - Definition of inducer tissues
Session 4:
- Three-dimensional embryos - Branchiomery - Systems for specific exchanges with the external world: . Birds . Mammals . Multiple gestation
Session 5:
- Cell bases for morphogenesis - Adhesion or environment-analysis molecules - Development genes |
 |  | General Genetics |

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 | - Defining the organization of genes. Defining intragenic and extragenic DNA. Understanding prokaryotic and eukaryotic genomic structures.
- Understanding the rules for the hereditary transmission of simple genetic characters. Understanding genetic recombination mechanisms.
- Understanding the notion of quantitative trait. Assessing interactions between genes and the environment for the determination of complex traits. Understanding methods for exploring the role of heredity in the determination of complex traits and pathologies.
- Understanding how intra- or interpopulation genetic variations can be observed. Mastering and applying the Hardy-Weinberg law. Mastering and understanding how to modify the Hardy-Weinberg balance. |
 |  | Introduction to Human Anatomy |

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 | The goals of that course are multiple: -first: to give an overview of the general architecture of the human body to allow a good undserstanding of the principal physiological processes -second: to give an integrative view of the anatomy -third: to train the student with the 3D vision of the human body and its components by the use of the descriptive tools (from old tool (as section, schemes...) to niew tools (computer assisted imaging, 3D reconstruction) |
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| Prerequisites :
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 |  | General biology preparing to biomedical and dental sciences, including introduction to molecular biology |

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 | The course will not overlook the significant differences between 1st-year students from very different backgrounds. |
 |  | Introduction to Human Anatomy |

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 | None |
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| Workshops :
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 |  | General biology preparing to biomedical and dental sciences, including introduction to molecular biology |

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 | Practicals are intended to show students a number of plant and animal cells and organisms and introduce different instruments and techniques (microscopy, drawing, dissection
) as well as observation and experimentation methods. They should also give everyone the opportunity to check theoretical knowledge against a personal, more experimental approach of the living world. Practicals are organized on Tuesday or Wednesday mornings (8:30am to 12:00pm), alternately with Biostatistics exercises. Location: Institut de Zoologie, 22 quai Van Beneden, 4020 LIEGE. Repetition sessions will be held to allow students to ask questions on the theoretical course as well as on practical exercises and help them to assimilate the different chapters of their Biology, Genetics and Embryology courses. |
 |  | Introduction to Human Anatomy |

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 | Demonstrations are organized in 5 occurences (10 for medical students). Participation is mendatory |
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| Organization :
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 |  | General biology preparing to biomedical and dental sciences, including introduction to molecular biology |

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 | In the first term, on Mondays from 1:00pm to 3:00pm. In the second term, on Wednesdays from 3:45pm to 5:45pm and Thursdays from 1:00pm to 3:30pm. |
 |  | General Embryology |

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 | The course is taught in the second term. Schedules and rooms will be published in the vade mecum. |
 |  | General Genetics |

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 | Lecture in French + 1 repetition with exercises 10 hours, 2nd term +1 hour repetition at the end of the term On Fridays from 10:15am to 12:15am. |
 |  | Introduction to Human Anatomy |

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 | Schedul for each section will be published in the "vademecum" |
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| Written notes :
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 |  | General biology preparing to biomedical and dental sciences, including introduction to molecular biology |

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 | 1) Theoretical course Title: Biologie des cellules, des organismes et des populations (Evolution, diversité, écologie), Professor Castronovo, edition 2003-2004 On sale: Intercopy copy shop, rue du Sart Tilman 360, Liège (04/367 78 48) 2) Practicals Title: Guide de Travaux pratiques de Biologie animale et végétale On sale: Intercopy copy shop. Recommended reading: CAMPBELL N.A.: Biologie (Ed. De Boeck). |
 |  | General Genetics |

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 | Analyse Génétique Moderne by Griffiths, Gelbart, Miller & Lewontin, De Boeck Université. |
 |  | Introduction to Human Anatomy |

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 | A syllabus is published each year Available in december 2004 (new edition))
Reference book: General anatomy, core text ; Introduction à l'anatomie (Masson) |
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| Assessment :
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 |  | General biology preparing to biomedical and dental sciences, including introduction to molecular biology |

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 | In-Year Assessments Tests on practicals and/or repetition sessions, including related theoretical knowledge. Tests will include multiple-choice questionnaires, True/False questions with explanations and open questions so as to allow students to learn about the different question types and find out about the expected knowledge and understanding level. Such tests will account for 5 marks in the final total grade. Assessments during the exam period 1) First exam period
a) In-year practical tests: 5 marks b) Practical exam: 10 marks c) Written theoretical exam: 30 marks c) Oral exam: 25 marks
2) Second exam period Common practical exam and written theoretical exam for Biology, Genetics, Embryology and Anatomy courses for all students without a global exemption in Biology. |
 |  | General Embryology |

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 | Written test during the June biomedical sciences module: open questions, true/false questions and multiple-choice questions. |
 |  | General Genetics |

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 | Within the biology module. Written exam (multiple choice + true/false questions with explanations). |
 |  | Introduction to Human Anatomy |

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 | Evaluation is performed regarding the rules of each section and module using Multiple Choice Q, Open Q and Short Answer Q |
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| Contacts :
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 |  | General biology preparing to biomedical and dental sciences, including introduction to molecular biology |

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 | Chef de service (Head of Department) Chargé de cours (Junior Lecturer): Vincent CASTRONOVO on 04/366 24 79 Email: vcastronovo@ulg.ac.be Secretary: 04/366 24 80 Fax: 04/366 29 75
Institut Zoologique, salle de TP (Practical hall): Marie-José DEBATISSE and Peter JENKE on 04/366 50 97
Scientific supervision: France MELOT, coordinator, on 04/366 24 09 Akeila BELLAHCENE, Michaël CHAPLET, Cédric DETRY, Thibault DASSESSE on 04/366 25 56, Wendy GLENISSON on 0472/37 60 72, Siv Ly TRAN on 04/366 25 56 or 0494/05 68 99, Nor-Eddine SOUNNI on 04/366 24 01 |
 |  | General Genetics |

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 | Lecturer in charge
Bours Vincent, Professor CHU B35 Phone: 04-3668145 Email: vbours@ulg.ac.be
Secretary
Fertons Marianne
Phone: 04-3668145 Email: genetique.humaine@ulg.ac.be |
 |  | Introduction to Human Anatomy |

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 | Professor Dr P.BONNET - Service d'Urologie CHU Sart Tilman, Bât. B35 (phone.: 04/366.72.52; e-mail: P.Bonnet@chu.ulg.ac.be: for problems not relative to the course, for questions about the anatomy > please use the forum tool on the online course)
Secretaress :
Anatomie : Messieurs G.Dessers et A. Botte : rue de Pitteurs, institut d'anatomie , phone 04 366 51 51(2 et 3)
Mme G. POLAIN - Service d'Urologie - CHU Sart Tilman Bât.B35 (phone: 04/366.72.52) |
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| Remarks :
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 |  | Introduction to Human Anatomy |

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 | The course is now also supported by an online course. Each student as its own password an identifiant to login. Address can be found on the Ulg Website. All the informations about the online course can be found in the 2004-05 issue of the syllabus (december 04) |
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