2023-2024 / SBIM0496-2

Advanced techniques for diagnosis and prognosis

Duration

10h Th, 10h Pr, 40h Pers. Res.

Number of credits

 Master in biomedicine (120 ECTS)5 crédits 

Lecturer

Pascal De Tullio, Keith Durkin, François Jouret , Céline Kempeneers, Sabine Wislet, Nadia Withofs

Coordinator

Laurence Delacroix

Language(s) of instruction

English language

Organisation and examination

Teaching in the second semester

Schedule

Schedule online

Units courses prerequisite and corequisite

Prerequisite or corequisite units are presented within each program

Learning unit contents

This course is dedicated to present up-to-date approaches, including biological biomarkers and imaging methods, to diagnose and prognosticate human diseases.

Students will learn how genomics, proteomics and metabolomics may help identify novel diagnosis and prognosis biomarkers of human diseases. In addition, students will learn which statistical methods are primarily used for evaluating the clinical relevance of emerging diagnosis and prognosis biomarkers. Finally, students will hear about the role of novel imaging approaches, including positron-emission computed tomography (PET) and function magnetic resonance imaging (fMRI), in diagnosing and prognosticating human diseases. 

This course also details the benefits and limitations of studying stem cell biology to better understand the pathophysiology of human diseases.

Learning outcomes of the learning unit

At the end of this course, students will be able to discuss each step of (i) discovery, (ii) validation and (iii) impact determination of emerging biological and imaging biomarkers in various fields of human medicine, as well as to appreciate the use of stem cells to further characterize the pathophysiology of human diseases.

Prerequisite knowledge and skills

This course is dedicated to medical and biomedical students with a strong background in normal cell biology and physiology.

Planned learning activities and teaching methods

This course is mainly given ex cathedra, with additional references to renowned book chapters and reviews.

Journal-club sessions are organized at the end of the course, and implicate the active participation of the students.

Mode of delivery (face to face, distance learning, hybrid learning)

Blended learning


Additional information:

Face-to-face: this course is mainly given ex cathedra.

Distance-learning: the students are encouraged to read additional book chapters and reviews and to prepare in advance journal club sessions.

Recommended or required readings

Book chapters and up-to-date reviews are provided by each teacher at the beginning of each class.

Any session :

- In-person

oral exam

- Remote

oral exam

- If evaluation in "hybrid"

preferred in-person


Additional information:

The evaluation of this course is based on an oral presentation about one specific topic of the course chosen by the student (among a pre-established list of topics).
The criteria of evaluation include : - Oral presentation (15') (50 %)


  • Adequacy of coverage, knowledge and understanding
  • Quality of the English (oral mostly + written (slides))
  • Ability to convey a message, to communicate
 - Answers to questions from the jury (15') (50 %)


  • Understanding and quality of discussion
Depending on the sanitary context due to COVID-19, the oral exam may be organized on-site (green or orange code) or online through a specific Collaborate session (red code).

Work placement(s)

Organisational remarks and main changes to the course

Contacts

The teachers are J. Caers, L. Delacroix, K. Durkin, F. Jouret, et S Wislet

Association of one or more MOOCs