2023-2024 / INFO0954-1

Advanced biological data analysis

Duration

10h Th, 30h Mon. WS

Number of credits

 Master in bio-informatics and modelling (120 ECTS)5 crédits 

Lecturer

Patrick Meyer

Language(s) of instruction

English language

Organisation and examination

Teaching in the first semester, review in January

Schedule

Schedule online

Units courses prerequisite and corequisite

Prerequisite or corequisite units are presented within each program

Learning unit contents

This course introduces machine learning algorithms (neural networks, decision trees, Bayes classifiers,...) as well as meta-heuristics, especially the biologically inspired ones (genetic algorithms, ant colony optimization algorithms, simulated annealing,...). Many methods discussed here will be used in R in order to extract a gene signature from RNA-seq data.

Learning outcomes of the learning unit

Getting familiar with machine learning and bioinspired meta-heuristics basic principles, up to being able to use them in R.

Prerequisite knowledge and skills

Basic R knowledge should have already been acquired (for example through STAT0077 or OCEA0224, the biological data analysis courses).

Planned learning activities and teaching methods

An important part of the course will be devoted to the implementation of very simple examples in order to get familiar with algorithms functionning.

Mode of delivery (face to face, distance learning, hybrid learning)

Presential classes, exercises on computers during the classes as well as as homeworks.

Recommended or required readings

http://www.bioinfo.uliege.be/classes/INFO0954/

Reference

Statistics and Data Analysis for Microarrays Using R and Bioconductor (Chapman & Hall/CRC Mathematical and Computational Biology) 2nd Edition
by Sorin Draghici

Exam(s) in session

Any session

- In-person

oral exam

Written work / report


Additional information:

Oral presentation of a classical method or a scientific article, with additional theoretical question related to the course. An R project (as homework) will contribute to the evaluation.

Work placement(s)

Organisational remarks and main changes to the course

Contacts

Prof. Patrick Meyer,
BioSys Lab e-mail: Patrick.Meyer@uliege.be tel : 04366 3030

Association of one or more MOOCs

There is no MOOC associated with this course.