Study Programmes 2016-2017
WARNING : 2015-2016 version of the course specifications
BICP2211-2  
University programme
  • Seminars on medical chemistry
  • Seminars on microbiology and infectiology
  • Seminars on hematology
  • Seminars on medicamentous toxicology
  • Blood group serology
  • Biostatistics II
  • Multivariate statistical analysis
  • Study of the human genome in normal and pathological methods of molecular biology
  • Quality insurance
Duration :
Seminars on medical chemistry : 25h Th, 120h SEM
Seminars on microbiology and infectiology : 25h Th, 120h SEM
Seminars on hematology : 25h Th, 120h SEM
Seminars on medicamentous toxicology : 15h Th, 120h SEM
Blood group serology : 15h Th, 90h Pr
Biostatistics II : 15h Th, 15h Pr
Multivariate statistical analysis : 10h Th, 10h Pr
Study of the human genome in normal and pathological methods of molecular biology : 10h Th, 10h Pr
Quality insurance : 10h Th, 10h Pr
Number of credits :
Specialised master in clinical biology20
Specialised master in clinical biology20
Lecturer :
Seminars on medical chemistry : Collégialité
Seminars on microbiology and infectiology : Marie-Pierre Hayette, Pierrette Melin
Seminars on hematology : André Gothot
Seminars on medicamentous toxicology : Corinne Charlier
Blood group serology : Mélanie Monfort
Biostatistics II : Anne-Françoise Donneau
Multivariate statistical analysis : Anne-Françoise Donneau
Study of the human genome in normal and pathological methods of molecular biology : Vinciane Dideberg, Frédéric Lambert
Quality insurance : Collégialité
Coordinator :
N...
Language(s) of instruction :
French language
Units courses prerequisite and corequisite :
Prerequisite or corequisite units are presented within each program
Learning unit contents :
Seminars on microbiology and infectiology
Supplement of clinical microbiology through clinical cases.
Specific lectures covering pathologies not described during the first year (Tropical diseases, rare diseases, other).
Seminars on hematology
Hematology is the study of cellular and molecular elements of the blood. The course is dedicated to the physiopathology of hematological illnesses and the laboratory tests used for their diagnosis.
Seminars on medicamentous toxicology
Specific cursus on chromatographic methods in a clinical, forensic and environmental toxicology department.
The students will stay for a 2 - 3 monthes in the lab and participate to technical validations, protocol signatures, etc....
Biostatistics II
This course is the second part of the teaching of Biostatistics at the Faculty of Medicine. It addresses mre advanced statistical methods, such as regression, one-way and two-way analysis of variance (ANOVA), contingency tables and non-parametric statistical techniques.

Each lesson consists of a theoretical exposition of the method followed by a session of practical applications, where the student will get used to solve statistical problems encountered in daily practice.
Multivariate statistical analysis
The course is a general introduction to the descriptive methods and tests used in multivariate statistics, i.e. the study of several variables simultaneously. The course entails the following chapters:

- Short review of matrix calculus

- Graphical display of multivariate data

- Mean vector and dispersion matrix

- Principal component analysis

- Multiple regression and correlation

- Logistic and ordinal regressions

- Survival curves and Cox regression

- Discriminant analysis
Learning outcomes of the learning unit :
Seminars on microbiology and infectiology
At the end of the course, the future specialist will be able to
  • discuss clinical presentation and propose appropriate diagnostic analysis
  • interpret the results of microbiological analysis and provide relevant comments.
Seminars on hematology
1. physiology of hematopoiesis and normal blood cells
2. pathology of red blod cells
3. pathology of white blood cells
4. pathology of platelets
5. hemostasis and coagulation
Biostatistics II
The course is intended to improve and enhance the use of biostatistics in health sciences, by insisting on statistical reasoning and problem solving rather than on the mathematics and the complexity of formula. Students should be able to carry out an in-depth statistical analysis of a dataset resulting from an experiment or a survey, in particular with respect to the thesis they will prepare later on in their cursus.
Multivariate statistical analysis
The course is an introduction to the methods of multivariate data analysis. At the end of the course, the sudent should be capable of defining a multivariate problem, analysing the data and interpreting the results. He/she should also be able to understand the use of multivariate methods in the scientific literature.
Prerequisite knowledge and skills :
Seminars on microbiology and infectiology
First-year course
Seminars on hematology
Human and pathological biochemistry. Histology.
Biostatistics II
Students should have received the course "Biostatistics I" or some equivalent statistical course.
Multivariate statistical analysis
A good knowledge of univarite statistical methods.
Planned learning activities and teaching methods :
Seminars on microbiology and infectiology
Interpretation of clinical cases and comments upon scientific papers Ex-cathedra courses (specific topics)
Seminars on hematology
Ex cathedra lessons.
Biostatistics II
Total: 15 hours
In statistics, practice is most important. Students are therefore requested to attend the practicals. These will be scored and taken into account in the final score of the exam.
Practicals will start on Thursday 8 November 2012 at the Mathematic Institute, usually from 16h30 to 18h30. The last session will be on 13 December 2012.
Please take with you your lecture notes, exercise book, pocket calculator and a pad
Multivariate statistical analysis
The practical sessions consist in analysing mulltivariate datasets by means of the software package Statistica.
Mode of delivery (face-to-face ; distance-learning) :
Seminars on microbiology and infectiology
Face to face and distant learning
  • Interpretation of clinical cases (Tutorial groups)
  • Ex-cathedra short courses on specific topics
  • Review of scientific papers
Seminars on hematology
Face-to-face lessons.
Biostatistics II
The course will start on Thursday 8 November 2012 at 14h00 at the Auditorium 01 of the Mathematic Institute (Bldg B37, Pkg P32). In general, the course lasts until 16h30 with 10-15 break. The last course will be on 13 December 2012.
Multivariate statistical analysis
Each course consists of 1h30 of theory and 1h of exercises with Statistica. One lecture will be dedicated to Statistica (the corresponding manual has also to be acquired for 10 EUR). The homeworks can be completed at home by the student.
Recommended or required readings :
Seminars on microbiology and infectiology
Recommended books:
  • Lippincott's illustrated reviews-Microbiology 2d edition- R. Harvey and P. Champe Ed.
  • Moisissures-Dermatophytes-Levures. Chabasse D. et al. Biomérieux Ed. 2005
  • Médecine tropicale. Marc Gentilini. Flammarion Ed. 2012
  • Fungal infection. Diagnosis and management. Richardson and Warnock. Wiley-Blackwell Ed. 2012
  • Bactériologie médicale - Techniques usuelles  2ème édition  François DENIS, Marie-Cécile Ploy, Christian Martin, Edouard Bingen, Roland QUENTIN Editeur: Elsevier Masson. 11/2011 ISBN: 9782294096686 
  • Numerous files, papers concerning varied domains of microbiology can be found on the ASM website (American Society of Microbiology) A consulter et télécharger du site de l'ASM : http://clinmicro.asm.org/index.php/bench-work-resources
  • The  Cumitech series provides consensus recommendations regarding the judicious use of clinical microbiology and immunology laboratories and their role in patient care. Each Cumitech is written by a team of clinicians, laboratorians, and other interested stakeholders to provide a broad overview of various aspects of infectious disease testing. These aspects include a discussion of relevant clinical considerations; collection, transport, processing and interpretive guidelines; the clinical utility of culture-based and non-culture-based methods and emerging technologies; They are edited and published by the ASM.
Seminars on hematology
Distribution of slides presented during the lessons.
Biostatistics II
Students will have to buy the lecture notes "Biostatistics, A. Albert, edition 2012" at Point de Vue shop near the large lecture halls at the cost of 15 EUR. This book contains the course material as well the main statistical tables. It will be used during exercise sessions and at the final examination. Finally, it can be used as a reference book in biostatistics in subsequent years.

NB. Students who bought the Biostatistics lecture notes in 1.Bachelor year can use it!
Textbook D.G. Altman. Practical statistics for medical research. Chapman & Hall, London, 2000.
Multivariate statistical analysis
Students will have to buy the lecture notes "Multivariate statistical analysis", A. Albert, edition 2011" at Editions de l'Université de Liège for 15 EUR. This book contains the course material as well the main statistical tables. It will be used during exercise sessions and at the final examination. Finally, it can be used as a reference book in multivariate statistics in subsequent years, in particular for the final project.
Textbooks are: - Multivariate statistical methods. D. Morrison, Mc Graw-Hill, Auckland, 1986 - Introduction to multivariate analysis. C. Chatfield et A.J. Collins, Chapman and Hall. ed, London, 1980
Assessment methods and criteria :
Seminars on microbiology and infectiology
Oral exam
Presentation of a clinical case
Active involvement during lectures and workshops
Seminars on hematology
Oral exam by opened questions selected among a list communicated to the students at the end of the course. True/false questions on the whole course content.
Biostatistics II
A written test will take place in January. Any score of 10 or more will be considered as a success, exempting the student from the examination in June or September. All exams are written exams and students can used their lectures notes or any other documents. Exams are scored 0-20.
Multivariate statistical analysis
Written examination.
Work placement(s) :
Seminars on microbiology and infectiology
6 month internship in microbiology within the first 2 years of master in clinical biology
Organizational remarks :
Multivariate statistical analysis
The course will normally take place on Wednesday afternoon of the fisrt quadrimester in the auditoria of the University hospital (CHU). Please make sure to chek the name of lecture room before the course starts because it could change from one lecture to another.
Contacts :
Seminars on microbiology and infectiology
 
Clinical Microbiology Department University Hospital of Liège, B-23 Sart Tilman, 4000 LIEGE Belgium Secretary
For any contact or to fix an appointment, please contact the secretary Mrs MC Lhote
Professors and lecturers Prof. Pierrette Melin Pierrette.Melin@ulg.ac.be
Prof. Marie-Pierre Hayette, mphayette@ulg.ac.be(mphayette@chu.ulg.ac.be )
Julie Descy, Pharmacist specialist in clinical biology julie.descy@chu.ulg.ac.be
Pascale Huynen, MD specialist in clinical biology p.huynen@chu.ulg.ac.be
Cécile Meex, Pharmacist specialist in clinical biology c.meex@chu.ulg.ac.be(p.huynen@chu.ulg.ac.be)
Seminars on hematology
Hematobiology and Immuno-Hematology

CHU, Tower 2, 6th floor, room 19.

Tel: 04/366 75 36 (Mrs Henet)

e-mail: hematobio@ulg.ac.be
Seminars on medicamentous toxicology
Prof. Corinne CHARLIER
Service de toxicologie clinique, médicolégale, de l'environnement et en entreprise
Bloc central +3 porte 166 CHU
Tél secrétariat 04/3667683 (B.Cornet)Toxclimedileg@chu.ulg.ac.be
Assistants : Raphaël DENOOZ, Virginie MISTRETTA
Biostatistics II
Lecturer Adelin ALBERT (Professeur ordinaire), Département des Sciences de la Santé Publique (DSSP)- Informatique Médicale et Biostatistique, CHU Sart Tilman (B35), 4000 Liège. Tél: 04-366.25.91/90 - Fax: 04-366.25.96 Email: aalbert@ulg.ac.be
Secretary Mrs Anna MARCHETTA, Département des Sciences de la Santé Publique (DSSP)- Informatique Médicale et Biostatistique (IMBS), CHU Sart Tilman (B35), 4000 Liège. Tél: 04-366.25.90 - Fax: 04-366.25.96 Email: imbs@ulg.ac.be
Assistants Laurence SEIDEL-VERMEERSCH (coordination) Tél: 04-366.25.95 - Email: Laurence.Seidel@ulg.ac.be

Anne-Françoise DONNEAU Tél: 04-366.47.90 - Email: afdonneau@ulg.ac.be

Nadia DARDENNE Tél: 04-366.33.40- Email: ndardenne@ulg.ac.be
Multivariate statistical analysis
Lecturer

Adelin ALBERT (Professeur ordinaire), Département des Sciences de la Santé Publique (DSSP)- Informatique Médicale et Biostatistique, CHU Sart Tilman (B35), 4000 Liège. Tél: 04-366.25.91/90 - Fax: 04-366.25.96 Email: aalbert@ulg.ac.be

Secretary

Anna MARCHETTA, Département des Sciences de la Santé Publique (DSSP)- Informatique Médicale et Biostatistique (IMBS), CHU Sart Tilman (B35), 4000 Liège. Tél: 04-366.25.90 - Fax: 04-366.25.96 Email: imbs@ulg.ac.be

Assistant

Anne-Françoise DONNEAU
Tél: 04-366.47.90 - Email: afdonneau@ulg.ac.be