CHIM9291-1 : structural analysis

Study Programmes 2015-2016

CHIM9291-1

structural analysis

Duration :

45h Th

Number of credits :

Bachelor in chemistry		4
Bachelor in chemistry		4
Master in chemistry (120 ECTS)		4
Master in chemistry (60 ECTS)		4

Lecturer :

Christian Damblon, Edwin De Pauw

Coordinator :

Edwin De Pauw

Language(s) of instruction :

French language

Organisation and examination :

Teaching in the second semester

Units courses prerequisite and corequisite :

Prerequisite or corequisite units are presented within each program

Course contents :

The course emphasises the complementarities of spectroscopic methods for the identification of organic molecules. The methods described are Mass Spectrometry, Infrared spectroscopy, UV-Visible spectroscopy and Nuclear Magnetic resonance. Methods are introduced one by one and illustrated by exercises that require coupling methods for their resolution. NMR is an important chapter. It includes 1H and 13C RMN as well as 2D RMN. Examples also concern organometallic compounds with non-zero spin central atoms. Exercises resolution and self-training is essential all along the course.

Learning outcomes of the course :

The objectives of the course are to gather the theoretical and experimental tools necessary to the determination of the structure of organic, organometallic and biological molecules and to describe the method of optimal use of spectroscopic information to determine an univocal structure, at least until connectivities.

Prerequisite knowledge and skills :

General Organic Chemistry
General Physical Chemistry

Planned learning activities and teaching methods :

Practical exercises of problems resolution. The level of difficulty increases in synchronization with the techniques gradually seen during the theory lessons, under the supervision of an assistant. These exercises prepare with a working method allowing a correct management of time and information.

Mode of delivery (face-to-face ; distance-learning) :

Reference books More Spectroscopic Problems in Organic Chemistry (Spectroscopy in Chemical Education, Baker et al, Heyden, 1967) Organic Structure from Spectra (Sternell et Kalman, Wiley, 1987) Spectrometric Identification of Organic Compounds (Silverstein, Bassler et Morill, Wiley, Ed7, 2005)