Study Programmes 2015-2016
| BIOC0722-1 | |||||||||||
| Application of spectroscopic techniques to the study of folding and stability of proteins | |||||||||||
|
Duration :
|
|||||||||||
| 20h Th, 10h Mon. WS | |||||||||||
|
Number of credits :
|
|||||||||||
|
|||||||||||
|
Lecturer :
|
|||||||||||
| André Matagne | |||||||||||
|
Language(s) of instruction :
|
|||||||||||
| French language | |||||||||||
|
Organisation and examination :
|
|||||||||||
| Teaching in the second semester | |||||||||||
|
Units courses prerequisite and corequisite :
|
|||||||||||
| Prerequisite or corequisite units are presented within each program | |||||||||||
|
Course contents :
|
|||||||||||
| This series of lectures is based on the use of biophysical methods (mainly optical spectroscopies, presented into details for course BIOC0721-1: Propriétés optiques des macromolécules biologiques) to study protein folding. Concrete examples (e.g. bêta-lactamases, single-domain antibody fragments, lysozymes) are analyzed in details, on the basis of theoretical background and data found in the literature. | |||||||||||
|
Learning outcomes of the course :
|
|||||||||||
| Students will learn how biophysical methods can be used to study protein folding. | |||||||||||
|
Prerequisite knowledge and skills :
|
|||||||||||
|
Planned learning activities and teaching methods :
|
|||||||||||
| Lectures are given with the help of powerpoint presentations, blackboard and white chalk | |||||||||||
|
Mode of delivery (face-to-face ; distance-learning) :
|
|||||||||||
| Face-to-face only | |||||||||||
|
Recommended or required readings :
|
|||||||||||
| Scientific articles will be given as they are analyzed and lecture notes will be available following the lectures | |||||||||||
|
Assessment methods and criteria :
|
|||||||||||
| An oral will be organized. Each student is given ca. 30 min, with maximum 15 min for preparation and thus minimum 15 min for discussion. | |||||||||||
|
Work placement(s) :
|
|||||||||||
|
Organizational remarks :
|
|||||||||||
| Lectures will be organized following the schedule known by the students. The professor will inform the students in advance of any possible modification to this | |||||||||||
|
Contacts :
|
|||||||||||
| André Matagne, PhD, Professor, Enzymology and Protein Folding, Centre for Protein Engineering, Life Science Department, Institut de Chimie B6c (room 3/1), Allée de la Chimie, 3, University of Liège, B4000 Liège (Sart-Tilman), Tel.: +32 (0)4 3663419, Fax: +32 (0)4 3663396, Email: amatagne@ulg.ac.be | |||||||||||