Study Programmes 2015-2016
BIOC0716-1  
Antibiotic resistance
Duration :
25h Th, 25h Pr
Number of credits :
Master in biochemistry and molecular and cell biology (120 ECTS)5
Master in biochemistry and molecular and cell biology (120 ECTS)5
Lecturer :
Moreno Galleni, Frédéric Kerff, Mohammed Terrak
Coordinator :
Moreno Galleni
Language(s) of instruction :
French language
Organisation and examination :
Teaching in the first semester, review in January
Units courses prerequisite and corequisite :
Prerequisite or corequisite units are presented within each program
Course contents :
During this thematic week, the different resistance mechanisms developed by bacteria against the different classes of clinically used antibiotics will be reviewed. A particular focus will be made on bacterial resistance towards aminoglycosides and inactivators of the enzymes involved in the biosynthesis of the bacterial cell wall. The different mechanisms of propagation of the resistance genes will be discussed and their potential biological cost analysed. The methods designed for the rapid detection of resistance mechanisms will be presented. Finally, the techniques recently developed for the design or high throughput screening of new antibiotics will be discussed.
Learning outcomes of the course :
Prerequisite knowledge and skills :
Planned learning activities and teaching methods :
Mode of delivery (face-to-face ; distance-learning) :
25 hours of teaching during one week

languages: french/ english
Recommended or required readings :
Power point presentation + overheads
Assessment methods and criteria :
The evaluation will be based on the presentzation and discussion of an original published article.
Work placement(s) :
Organizational remarks :
Contacts :
Prof. Galleni Moreno
Lab. Macromolécules Biologiques
Centre d'Ingénieire des Protéines
Local 2.10. Institut de Chimie B6a
Sart Tilman
mgalleni@ulg.ac.be
Tel 04/366 35 49
Fax 04/366 33 64



Prof. Joris Bernard
Centre d'Ingénieire des Protéines
B6a- Institut de Chimie - Sart Tilman
bjoris@ulg.ac.be



(bjoris@ulg.ac.be)