Study Programmes 2015-2016
| ANIM0003-1 | ||||||||
| Immunology and immunochemistry | ||||||||
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Duration :
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| 12h Th, 12h Pr | ||||||||
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Number of credits :
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Lecturer :
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| Daniel Portetelle | ||||||||
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Language(s) of instruction :
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| French language | ||||||||
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Organisation and examination :
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| Teaching in the second semester | ||||||||
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Units courses prerequisite and corequisite :
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| Prerequisite or corequisite units are presented within each program | ||||||||
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Course contents :
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| . Overview of the immune system: historical perspective, innate immunity, acquired immunity . Cells and organs of the immune system: hematopoiesis, CD antigens, cells and organs, antigen-presenting cells, dendritic cells, leucocytes migration and homing; . Generation of B-cell and T-cell responses: antigens; immunoglobulins: structure and function; antigen-antibody interactions; principles and applications; organization and expression of immunoglobulin genes; antibody engeneering; B-cell maturation activation and differentiation; major histocompatibility complexes; antigen processing and presentation; T-cell receptor, T-cell maturation, activation and differentiation; Immune effector mechanisms: cytokines; . cell-mediated and humoral effector responses; regulation of the immune effector response . Other aspects of immunity (overview): immunodeficiency, tolerance, autoimmunity, hypersensitive reactions, inflammations, external factors, vaccinology (for more details, see ANIM0009-A-Immunobiology) . Practical works: productions of antibodies, precipitation reactions, agglutination reactions, the complement system and its applications, radioimmunoassay, enzyme-linked immunosorbent assay, overview of other modern immunochemical techniques. | ||||||||
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Learning outcomes of the course :
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| Acquisition of the molecular and cellular bases of immunology. Supply of requisite informations on mechanisms and main current and prospective applications. After completing the course the student is expected to - understand the mechanism of the immune system of the being alive - integrate the immunochemical approach in detection systems of molecules of some importance |
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Prerequisite knowledge and skills :
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| BIOL2015 - Molecular biology
BIOL2011 - Comparative animal anatomy and physiology |
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Planned learning activities and teaching methods :
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Mode of delivery (face-to-face ; distance-learning) :
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| Lectures : 12h Practical Works : 12h |
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Recommended or required readings :
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| Kuby Immunology (Owen, Punt, Stranford), 7°ed, 2013, W.H. Freeman, New York, 800 pages
Immunologie: le cours de J.Kuby: french translation of the 7th ed. by C. Friedman, DUNOD, Paris, 2014, 800 pages.
Text notes (PowerPoint) available on line. |
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Assessment methods and criteria :
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| Continuous written assessment as true or false answers to simple questions. | ||||||||
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Work placement(s) :
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Organizational remarks :
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Contacts :
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| Portetelle, Daniel (Professeur ordinaire - Chef de service) Microbiologie et Génomique 081 62 23 54 daniel.portetelle@ulg.ac.be | ||||||||
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Items online :
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 | Notes on line PowerPoint available on ecampus. |
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