 | | |
| Version 2013-2014 |
|
| SEXL0120-1 | Multidisciplinary approach to the genital system
|
|
| Duration : | 40h Th |
|
| Number of credits : |
|
|
| Lecturer : | Pierre Bonnet, Jean-Pierre Bourguignon, Alain Carlier, Vincent Geenen, Philippe Kolh, Michelle Nisolle, Pascale Quatresooz |
|
| Coordinator : | Sophie Perrier d'Hauterive |
|
Language(s) of instruction :
|
| French language |
|
Course contents :
|
| Physiology in reproductive medicine
- Hypothalamo-pituitary axis function
- Ovarian cycle
- Menstrual cycle
- Fecondation and embryonic implantation
- Adapatations and physiological modifications associated to pregnancy
- Normal delivery: foetus and placenta
- The placenta, the cord and the membrans
- Maternal breast feeding
|
|
Learning outcomes of the course :
|
|
- Describe the role of hypothalamus in ovulation induction
- Describe the hypothalamic neuro-endocrine system
- Describe the relations between the hypothalamus and the pituitary gland
- Understand the importance of the pulsatility of GnRH secretion
- Describe the pulsatility of the GnRH during the cycle
- Describe the clinical consequences of continuous administration of GnRH
- Schematize the hypothalamo-pituitary secretions in relation with the ovarian and menstrual cycles
- Knowledge of the external and internal regulation of the hypothalomo-pituitary axis
- Describe the steroidal feedback on the hypothalamo-pituitary axis
- Describe the role of the pituitary hormones on the ovulation induction
- Describe the follicular growth until the ovulation
- Describe the different phases of the ovarian cycle and variations
- Describe endocrine and exocrine functions of the ovary
- Knowledge of the inhibines role on the ovarian cycle
- Knowledge the follicular atresia and the importance
- Describe the bi-cellular theoric of the steroidal ovarian secretion
- Describe the different steps of the steroidal hormones synthesis
- Describe how to determine the ovarian reserve
- Describe the mecanisms responsible of the ovulation
- Precise the role of the corpus luteum
- Compare the peripheric effects of the progesterone and oestrogens
- Explain the consequences of oestrogens exces
- Describe and compare the different phases of the menstrual cycle
- Explain the initiation of the menstruations
- Describe the embryo implantation and trophoblastic invasion
- Describe the relation between the ovarian cycle and the menstrual cycle
- Describe the implantation window and its importance
- Describe the different possibilities to evaluate the clinical impregnation on oestrogens and progesterone
- Explain the importance of the LH-RH test in amenorrhea
- Explain the different possibilities to explore the ovarian function
- Explain the irregular cycles at the puberty and peri-menopausis
- What are the hormonal analysis needed to diagnose the menopausis
- Explain the role of the progesterone test
- Explain the mecanism of the hormonal contraception
- Describe the role of the foeto placental unit in the steroids production
- Explain the hormones producted by the placenta and the role of the human chorionic gonadotrophin (hCG)
- Describe the mecanisms of the delivery
- Describe the lactation mecanism
- Knowledge of the anatomy and histology of the placenta
- Knowledge of the uterine contraction, consequences on the cervix and the dilatation
- Knowledge of the different physiological maternal modifications in relation with the pregnancy
- Knowledge of the steps of the pulmonary maturation and its clinical implication
- Knowledge of the myometrial histology, main receptors on muscular fibers and the physiology of the contraction
- Knowledge of the mammal gland outside and during the pregnancy and the lactation
- Knowledge of the formation of amniotic liquid and its role
- Knowledge of the insuline resistance during pregnancy
- How to detect the gestational diabetis
- Knowledge of the foetal consequences of the hyperglycemia
- Knowledge of the cinetic and the regulations of the prolactin liberation
- Knowledge of the main signs of aneuploidia
- Knowledge of the different types of twin pregnancies
- Knowledge of the mecanism of the placental explusion
- Knowledge of the modifications of the uterus during pregnancy
- Knowledge of the cervical modification during labor
- Pelvic anatomy during pregnancy and delivery
|
|
Prerequisites and co-requisites/ Recommended optional programme components :
|
|
- Anatomy of the hypothalamo-pituitary system and of the female genital tract
- Histology of the female genital tract
- Embryology of the female genital tract
|
|
Planned learning activities and teaching methods :
|
| |
|
Mode of delivery (face-to-face ; distance-learning) :
|
| Ex-Cathedra courses: 8x2 hours
- Hypothalamo-pituitary axis function
- Ovarian cycle
- Menstrual cycle
- Fecondation and embryonic implantation
- Adapatations and physiological modifications associated to pregnancy
- Normal delivery: foetus and placenta
- The placenta, the cord and the membrans
- Maternal breast feeding
|
|
Recommended or required readings :
|
| Courses notes available |
|
Assessment methods and criteria :
|
| QROC and QCM
Oral evaluation: complete evaluation of the genital module knowledge |
|
Work placement(s) :
|
| |
|
Organizational remarks :
|
| |
|
Contacts :
|
| Professor Michelle NISOLLE
michelle.nisolle@chu.ulg.ac.be
Secretary:
Barbara DENEUMOSTIER
barbara.deneumostier@chrcitadelle.be |
|
