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| Version 2013-2014 |
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| SBIM0495-1 | Molecular and cellular basis of disease
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| Duration : | 20h Th, 10h Mon. WS, 40h Pers. Res. |
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| Number of credits : |
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| Lecturer : | Collégialité, Vincent Seutin |
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Language(s) of instruction :
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| English language |
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Organisation and examination :
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| Teaching in the first semester, review in January |
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Course contents :
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| This course details the different cellular and tissular mechanisms classically involved in the pathophysiology of human diseases.
Based on the concepts of normal cell biology and physiology reviewed in Course 1 (SBIM0494), this course is divided into 5 main sections according to the main causes of human diseases:
- Genetic perturbations
- Dysfunction of nuclear receptors
- Protein misfolding and aggregation
- Alteration of membrane proteins
- Alteration in the regulation of cell functions
Each class is given by a specific teacher according to his/her area of expertise. |
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Learning outcomes of the course :
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| At the end of this course, students should be able to apprehend the main cellular and tissular mechanisms involved in the pathophysiology of human diseases. |
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Prerequisites and co-requisites/ Recommended optional programme components :
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| This course is dedicated to medical and biomedical students with a strong background in normal cell biology and physiology. |
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Planned learning activities and teaching methods :
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| This course is mainly given ex cathedra, with additional references to renowned book chapters and reviews.
Journal-club sessions are organized at the end of the course, and implicate the active participation of the students. |
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Mode of delivery (face-to-face ; distance-learning) :
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| Face-to-face: this course is mainly given ex cathedra.
Distance-learning: the students are encouraged to read additional book chapters and reviews and to prepare in advance journal club sessions. |
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Recommended or required readings :
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| Book chapters and up-to-date reviews are provided by each teacher at the beginning of each class. |
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Assessment methods and criteria :
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| The evaluation of this course is based on an oral presentation about one specific topic of the course choosen by the student (among a pre-established list of topics).
The criteria of evaluation include :
- Proactivity during lectures (20 %)
- Oral presentation (15') (50 %)
- Adequacy of coverage, knowledge and understanding
- Quality of the English (oral mostly + written (slides))
- Ability to convey a message, to communicate
- Answers to questions (15') (30 %)
- Understanding and quality of discussion
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Work placement(s) :
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| None |
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Organizational remarks :
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| The teachers are : K. Durkin, L. Delacroix, Ch. Cornil, M. Dumoulin and S. Wislet, V. Seutin, J. Hanson, S. Sayyed, J. Caerts, P. Close and N. Rocks. |
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Contacts :
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| V. Seutin : V.Seutin@ulg.ac.be |
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