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| SBIM0462-1 | Pharmacology and addiction clinic
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| Duration : | 10h Th |
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| Number of credits : |
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| Lecturer : | Emmanuel Pinto |
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Language(s) of instruction :
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| French language |
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Organisation and examination :
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| Teaching in the first semester, review in January |
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Course contents :
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| The main purpose of this course is to provide students with the molecular mechanisms shared by the addictive disorders (neuro-anatomy of the reward circuits of the brain, molecular, genomic and structural adaptation linked to addiction).
We also review the main addictive substances on a pharmacological, epidemiolocal, clinical and theapeutic point of view.
Alcohol dependance is more precisely studied under its genetic, clinical and therapeutic specificities. |
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Learning outcomes of the course :
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| The objective is to give the student a general overview of the common neurobiological mechanisms shared by the main addictions.
Key-informations about the main addictive substances is a secondary objective of this course. |
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Prerequisites and co-requisites/ Recommended optional programme components :
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Planned learning activities and teaching methods :
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| Ex cathedra courses with Powerpoint support.Key articles provided |
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Mode of delivery (face-to-face ; distance-learning) :
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| Face-to-face |
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Recommended or required readings :
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| Powerpoint presentationKey-articles :
- Bowirrat, A., & Oscar-Berman, M. (2005). Relationship between dopaminergic neurotransmission, alcoholism, and Reward Deficiency syndrome. Am J Med Genet B Neuropsychiatr Genet(1), 29-37.
- De Witte, P., Pinto, E., Ansseau, M., & Verbanck, P. (2003). Alcohol and withdrawal : from animal research to clinical issues. Neurosci Biobehav R(27 ), 189-197.
- Koob, G. F., & Le Moal, M. (1997). Drug Abuse: Hedonic Homeostatic Dysregulation. Science, 278(5335), 52-58.
- Young, R. M., Lawford, B. R., Nutting, A., & Noble, E. P. (2004). Advances in molecular genetics and the prevention and treatment of substance misuse: Implications of association studies of the A1 allele of the D2 dopamine receptor gene. Addictive Behaviors, 29(7), 1275-1294.
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Assessment methods and criteria :
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| Multiple choices questionnaire |
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Work placement(s) :
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Organizational remarks :
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Contacts :
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| epinto@ulg.ac.be |
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