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| Version 2013-2014 |
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| ENVT3016-1 | Environmental toxicology and health
- Part 1 : Ecotoxicology and quantification of ecotoxicological risk
- Part 2 : Environmental toxicology and health impacts
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| Duration : | Part 1 : Ecotoxicology and quantification of ecotoxicological risk : 24h Th, 18h Pr
Part 2 : Environmental toxicology and health impacts : 12h Th, 18h Pr
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| Number of credits : |
| Master in sciences and environment management | | 6 |
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| Master en sciences et gestion de l'environnement, à finalité spécialisée en développement durable, 1st year | | 6 |
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| Master en sciences et gestion de l'environnement, à finalité spécialisée en procédé biologique de valorisation des effluents, 1st year | | 6 |
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| Master en sciences et gestion de l'environnement, à finalité spécialisée en énergies renouvelables, 1st year | | 6 |
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| Master en sciences et gestion de l'environnement, à finalité spécialisée en intervention technique, 1st year | | 6 |
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| Master en sciences et gestion de l'environnement, à finalité spécialisée pays en développement, 1st year | | 6 |
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| Master en sciences et gestion de l'environnement, à finalité spécialisée en gestion intégrée des ressources en eau, 1st year | | 6 |
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| Master en sciences et gestion de l'environnement, à finalité spécialisée en interfaces sociétés-environnements, 1st year | | 6 |
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| Master en sciences et gestion de l'environnement, à finalité spécialisée en surveillance de l'environnement, 1st year | | 6 |
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| Master en sciences et gestion de l'environnement, à finalité spécialisée en procédés biologiques de valorisation des déchets, 1st year | | 6 |
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| Lecturer : | Part 1 : Ecotoxicology and quantification of ecotoxicological risk : Célia Joaquim-Justo
Part 2 : Environmental toxicology and health impacts : Corinne Charlier
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| Coordinator : | Célia Joaquim-Justo |
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Language(s) of instruction :
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| French language |
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Course contents :
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| see french version
 | | Part 1 : Ecotoxicology and quantification of ecotoxicological risk |
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| The parameters for determining the fate of pollutants in the biosphere (transport, partition, degradation) and at the organization level (accumulation, redistribution in organs, metabolism, detoxification and elimination) will be presented.
The study of the effects of pollutants on organisms will be detailed (ecotoxicological tests that define the toxicity of substances, dose-response relationships, mechanisms of action at the molecular, cellular, tissue, physiological, organismal and population levels). Interactions of various pollutants and their impact on their effects on organisms will also be discussed.
Current tools for assessing pollution-related disturbances will be presented (monitoring and biomarkers). To illustrate these concepts, ecotoxicological tests will be conducted by the students so that they take the measure of the power and limitations of methods for assessing the toxicity of substances. We also propose to introduce students to the principles that govern the quantitative assessment of risk from chemicals, as realized in the EU (European Union), and provide the basics that allow this evaluation.
After an introduction to the principles on which the quantification of risk is based, techniques for estimating emissions and pollutant concentrations expected in the environment will be exposed. These such models, some of which will be detailed (McKay, EUSES, ...). The evaluation of the toxicity threshold of substances with respect to organisms in different compartments of terrestrial and aquatic ecosystems will also be detailed. Finally, the decision procedures based on risk assessment will be reviewed. To illustrate these concepts, we will take the environmental risk analysis (Ecological Risk) of chemicals or proposed for the industrial production based on actual cases. Based on these exercises, students will be assigned case studies in order to put them in the position of the expert toxicologist, in order to make them aware of the key elements in decision-making by experts ( precautionary principle versus realistic assessment of risk) as well as areas where improvements are still to be developed. |
| | Part 2 : Environmental toxicology and health impacts |
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| After the introduction, dedicated to history of toxicology, we will study:
1) different ways of entrance in body for chemicals
2) toxicokinetic : ADME
3) toxicodynamic principles
4) risk assessment (TLV, symbols, NOEl, TDI, ...)
5) monography of main toxics
6) quantification methods |
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Learning outcomes of the course :
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| | Part 2 : Environmental toxicology and health impacts |
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| We will try to give to the students some general knowledge about toxicology, with a particular attention to some definitions and to the main principles included in the risk definition for a chemical substance |
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Prerequisites and co-requisites/ Recommended optional programme components :
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Planned learning activities and teaching methods :
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| | Part 1 : Ecotoxicology and quantification of ecotoxicological risk |
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| The course will include lectures, practical sessions in the laboratory and real case studies prepared and exposed to all other students by groups of students. |
| | Part 2 : Environmental toxicology and health impacts |
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| Ex cathaedra cursus |
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Mode of delivery (face-to-face ; distance-learning) :
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| | Part 1 : Ecotoxicology and quantification of ecotoxicological risk |
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| Face-to-face |
| | Part 2 : Environmental toxicology and health impacts |
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| Lecture in ARLON by half days in second semester |
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Recommended or required readings :
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| | Part 1 : Ecotoxicology and quantification of ecotoxicological risk |
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| Principles of Ecotoxicology (Walker et al., Taylor & Francis)
Mechanistic toxicology (Boelsterli, Taylor & Francis)
Ramade 2007. Introduction à l'écotoxicologie: fondements et applications |
| | Part 2 : Environmental toxicology and health impacts |
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| Syllabus with main slides |
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Assessment methods and criteria :
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| | Part 1 : Ecotoxicology and quantification of ecotoxicological risk |
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| Evaluation of the general behaviour during the practical sessions in the laboratory and of the test report required.
Evaluation of the presentation of the real case study concerning the quantitative risk assessment (group work).
Written evaluation (final exam) |
| | Part 2 : Environmental toxicology and health impacts |
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| Written examination in june |
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Work placement(s) :
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Organizational remarks :
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Contacts :
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| | Part 1 : Ecotoxicology and quantification of ecotoxicological risk |
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| Dr. Joaquim-Justo
Laboratory of Animal Ecology & Ecotoxicology
Bât. B6c
Allée du 6 Août, n°11
4000 Liège
Tel: +32 4 366 51 40
e-mail: Celia.Joaquim-Justo@ulg.ac.be |
| | Part 2 : Environmental toxicology and health impacts |
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| Prof. Corinne CHARLIER
Clinical, forensic, environmental and industrial toxicology
Bloc central +3 porte 166 CHU
Phone (secretary: B.Cornet) : 04/3667683
Toxclimedileg@chu.ulg.ac.be
Assistants : Raphaël DENOOZ, Catherine PIRARD |
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| Items online : |
Part 1 : Ecotoxicology and quantification of ecotoxicological risk
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| Slideshows course and praticals |
| Slideshows course and praticals |
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