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| CHIM0213-2 | Structural analysis
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| Duration : | 45h Th |
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| Number of credits : |
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| Lecturer : | Christian Damblon, Edwin De Pauw |
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| Coordinator : | Edwin De Pauw |
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Language(s) of instruction :
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| English language |
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Organisation and examination :
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| Teaching in the first semester, review in January |
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Course contents :
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| The course emphasises the complementarities of spectroscopic methods for the identification of organic molecules. The methods described are Mass Spectrometry, Infrared spectroscopy, UV-Visible spectroscopy and Nuclear Magnetic resonance. Methods are introduced one by one and illustrated by exercises that require coupling methods for their resolution. NMR is an important chapter. It includes 1H and 13C RMN as well as 2D RMN. Examples also concern organometallic compounds with non-zero spin central atoms. Exercises resolution and self-training is essential all along the course. |
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Learning outcomes of the course :
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| The objectives of the course are to gather the theoretical and experimental tools necessary to the determination of the structure of organic, organometallic and biological molecules and to describe the method of optimal use of spectroscopic information to determine an univocal structure, at least until connectivities. |
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Prerequisites and co-requisites/ Recommended optional programme components :
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| General Organic Chemistry
General Physical Chemistry |
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Planned learning activities and teaching methods :
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| Practical exercises of problems resolution. The level of difficulty increases in synchronization with the techniques gradually seen during the theory lessons, under the supervision of an assistant. These exercises prepare with a working method allowing a correct management of time and information. |
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Mode of delivery (face-to-face ; distance-learning) :
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| Reference books
More Spectroscopic Problems in Organic Chemistry (Spectroscopy in Chemical Education, Baker et al, Heyden, 1967)
Organic Structure from Spectra (Sternell et Kalman, Wiley, 1987)
Spectrometric Identification of Organic Compounds (Silverstein, Bassler et Morill, Wiley, Ed7, 2005) |
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Recommended or required readings :
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| Reference books
More Spectroscopic Problems in Organic Chemistry (Spectroscopy in Chemical Education, Baker et al, Heyden, 1967)
Organic Structure from Spectra (Sternell et Kalman, Wiley, 1987)
Spectrometric Identification of Organic Compounds (Silverstein, Bassler et Morill, Wiley, Ed7, 2005) |
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Assessment methods and criteria :
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| Written exam. Knowlege and understanding of the theory and basic principle will be evaluated. the ability to apply the theory will be evaluated by the analysis of unknown compounds using multiple spectra |
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Work placement(s) :
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Organizational remarks :
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Contacts :
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| Pr. De Pauw Edwin
Institut de Chimie, Bât. B6, 4000 Liège 1, Sart Tilman
e-mail : e.depauw@ulg.ac.be
Pr. Christian Damblon
Institut de Chimie, Bât. B6, 4000 Liège 1, Sart Tilman
e-mail: c.damblon@ulg.ac.be
Nicolas Lamborelle, Assistant
e-mail:nlamborelle@ulg.ac.be |
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| Items online : |
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| cours 1-4 |
| Spectroscopie RMN pour l'analyse structurale |
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