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| Version 2013-2014 |
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| BIOL0004-1 | Biology of the reproduction
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| Duration : | 20h Th |
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| Number of credits : |
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| Lecturer : | Michelle Nisolle |
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Language(s) of instruction :
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| French language |
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Course contents :
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| Physiology in reproductive medicine
- Hypothalamo-pituitary axis function
- Ovarian cycle
- Menstrual cycle
- Fecondation and embryonic implantation
- Troubles of the ovulation
- Stimulation of the ovulation
- Preservation of the fertility
- Anomalies of the female and male genital systems
- Male reproduction system, anatomy and physiology
- Troubles of the male reproduction
- Technics of assisted medical procedures
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Learning outcomes of the course :
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- Describe the role of hypothalamus in ovulation induction
- Describe the hypothalamic neuro-endocrine system
- Describe the relations between the hypothalamus and the pituitary gland
- Understand the importance of the pulsatility of GnRH secretion
- Describe the pulsatility of the GnRH during the cycle
- Describe the clinical consequences of continuous administration of GnRH
- Schematize the hypothalamo-pituitary secretions in relation with the ovarian and menstrual cycles
- Knowledge of the external and internal regulation of the hypothalomo-pituitary axis
- Describe the steroidal feedback on the hypothalamo-pituitary axis
- Describe the role of the pituitary hormones on the ovulation induction
- Describe the follicular growth until the ovulation
- Describe the different phases of the ovarian cycle and variations
- Describe endocrine and exocrine functions of the ovary
- Knowledge of the inhibines role on the ovarian cycle
- Knowledge the follicular atresia and the importance
- Describe the bi-cellular theoric of the steroidal ovarian secretion
- Describe the different steps of the steroidal hormones synthesis
- Describe how to determine the ovarian reserve
- Describe the mecanisms responsible of the ovulation
- Precise the role of the corpus luteum
- Compare the peripheric effects of the progesterone and oestrogens
- Describe and compare the different phases of the menstrual cycle
- Explain the initiation of the menstruations
- Describe the embryo implantation and trophoblastic invasion
- Describe the relation between the ovarian cycle and the menstrual cycle
- Describe the implantation window and its importance
- Describe the different possibilities to evaluate the clinical impregnation on oestrogens and progesterone
- Explain the importance of the LH-RH test in amenorrhea
- Explain the different possibilities to explore the ovarian function
- Explain the irregular cycles at the puberty and peri-menopausis
- What are the hormonal analysis needed to diagnose the menopausis
- Explain the role of the progesterone test
- Explain the mecanism of the hormonal contraception
- Explain the hormones producted by the placenta and the role of the human chorionic gonadotrophin (hCG)
- Knowledge of the anatomy and histology of the placenta
- Describe the different methods of ovarian stimulation
- Knowledge of the recent data about the ovarian cryopreservation
- Describe the different anomalies of the female genital tract
- Describe the normal anatomy of the male genital tract and its anomalies
- Explain the different causes of the female infertility
- Explain the different causes of the male infertility
- Knowledge of the different technics of assisted medical procedures
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Prerequisites and co-requisites/ Recommended optional programme components :
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- Anatomy of the hypothalamo-pituitary system and of the female genital tract
- Histology of the female genital tract
- Embryology of the female genital tract
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Planned learning activities and teaching methods :
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Mode of delivery (face-to-face ; distance-learning) :
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| Ex-Cathedra courses: 10x2 hours
- Hypothalamo-pituitary axis function
- Ovarian cycle
- Menstrual cycle
- Fecondation and embryonic implantation
- Troubles of the ovulation
- Stimulation of the ovulation
- Preservation of the fertility
- Anomalies of the female and male genital systems
- Male reproduction system, anatomy and physiology
- Troubles of the male reproduction
- Technics of assisted medical procedures
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Recommended or required readings :
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| Powerpoint available |
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Assessment methods and criteria :
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| QROC |
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Work placement(s) :
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Organizational remarks :
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Contacts :
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| Professor Michelle NISOLLE
michelle.nisolle@chu.ulg.ac.be
Secretary:
Barbara DENEUMOSTIER
barbara.deneumostier@chrcitadelle.be |
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