University of Liege | Version française
Academic year 2014-2015Value date : 12/05/2015
Version 2013-2014
BIOI0002-1  Fermentation and extraction factories, 1st part

Duration :  24h Th, 24h Pr
Number of credits :  
Master in Chemistry and Bio-industries, Professional Focus, 1st year4
Advanced Master in Biotechnology and Applied Biology4
Lecturer :  Philippe Jacques
Language(s) of instruction :  
French language
Course contents :  
I. Introduction : the biotechnology
II. Growth kinetic
III. Biochemical balance
IV. Bioengineering
V. Optimization of biotechnological production.
VI. Downstream processing
VII. Examples of industrial production of starters.
VIII. The enzymes in agro-food industries.
Learning outcomes of the course :  
This course gives an overview of the principles used in industrial microbiology. The different steps necesary for doing a product are developped and integrated in a general production scheme. The exemples of enzymes and micro-organismes are developped.
After completing the course the student is expected to
- know the basic components of the bioreactor (vessel, pales, valves,
automation,...)
- perform basic calculation to design a bioprocess:
at the level of the microbial population (kinetic, mass balance,...)
at the level of the bioreactor (oxygen transfert efficiency, heat transfert
efficiency, mixing efficiency,...)
- perform the scale-up of a bioprocess
Prerequisites and co-requisites/ Recommended optional programme components :  
Knowledges in general microbiology and in biochemistry
Planned learning activities and teaching methods :  
Mode of delivery (face-to-face ; distance-learning) :  
Lectures : 24h
Practical Works : 24h
Recommended or required readings :  
Metabolic Engineering, Principles and Methodologies,Stephanopoulos et al., 1998, Academic Press
Biochemical Engineering,Blanch and Clark, 2003, Marcel Dekker, Inc(1993).
Assessment methods and criteria :  
Written examination (50%)
Oral examination (50%)
Work placement(s) :  
Organizational remarks :  
Contacts :  
Thonart, Philippe (Professeur Ordinaire)
Bio-industries
081 62 23 09
thonart.p@fsagx.ac.be

Items online :  
Notes on eCampus
Notes on eCampus



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