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| BIOC0721-1 | Optical properties of biological macromolecules
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| Duration : | 15h Th |
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| Number of credits : |
| Master in Biochemistry and Molecular and Cell Biology, Research Focus, 1st year | | 2 |
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| Master in Biochemistry and Molecular and Cell Biology, Teaching Focus, 1st year | | 2 |
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| Master en biochimie et biologie moléculaire et cellulaire, à finalité spécialisée en bio-industrie, 1st year | | 2 |
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| Master in Biochemistry and Molecular and Cell Biology, Professional Focus in
Industrial Biochemistry, 1st year | | 2 |
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| Master en biochimie et biologie moléculaire et cellulaire, à finalité spécialisée en bioinformatique et modélisation, 1st year | | 2 |
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| Master in Biological Sciences | | 2 |
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| Lecturer : | Christian Damblon, André Matagne |
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| Coordinator : | André Matagne |
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Language(s) of instruction :
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| French language |
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Organisation and examination :
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| Teaching in the first semester, review in January |
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Course contents :
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| The course presents the various optical methods used in biochemistry.
Spectroscopic methods taught i in the course will be : UV-Visible absorption, linear and circular dichroïsmes, fluorescence, vibrational spectroscopy (eg infrared and raman), surface plasmon resonance.
For each method, principles, technical aspects and applications focused on biological macromolecules will be developed.
The course will concludes with a review of the optical properties of proteins. |
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Learning outcomes of the course :
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| Increase the skills of the student regarding the available spectroscopic methods for the study of the conformational dynamics of biological macromolecules. |
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Prerequisites and co-requisites/ Recommended optional programme components :
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| Basic chemistry and physics |
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Planned learning activities and teaching methods :
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| Lectures are given with the help of powerpoint presentations, blackboard and chalk |
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Mode of delivery (face-to-face ; distance-learning) :
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| Face-to-Face only |
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Recommended or required readings :
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| Powerpoint presentations or lecture notes will be available following the lectures
Reference books:
- Biophysical Chemistry, Cantor & Schimmel
- Principles of Physical Chemistry, Van Holde et al.
- Biological Spectroscopy, Campbell & Dwek
- Physical Biochemistry, Sheehan |
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Assessment methods and criteria :
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| Student evaluation will be based on a written exam. |
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Work placement(s) :
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Organizational remarks :
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| Lectures will be organized following the schedule known by the students. The professor will inform the students in advance of any possible modification to this |
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Contacts :
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| Christian Damblon, Professor,
Department of Chemistry, Institut de Chimie B6c (room 3/71), Allée de la Chimie, 3, University of Liège, B4000 Liège (Sart-Tilman), Tel.: +32 (0)4 3663788, Fax: +32 (0)4 3663413,
E-mail : c.damblon@ulg.ac.be(P.Colson@ulg.ac.be
André Matagne, PhD, Professor, Enzymology and Protein Folding, Centre for Protein Engineering, Life Science Department, Institut de Chimie B6c (room 3/1), Allée de la Chimie, 3, University of Liège, B4000 Liège (Sart-Tilman), Tel.: +32 (0)4 3663419, Fax: +32 (0)4 3663396, Email: )amatagne@ulg.ac.be |
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