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| BIOC0719-2 | Enzymology
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| Duration : | 15h Th, 25h Pr |
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| Number of credits : |
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| Lecturer : | André Matagne |
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Language(s) of instruction :
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| French language |
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Organisation and examination :
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| Teaching in the first semester, review in January |
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Course contents :
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| Chapter 1: General properties of enzymes. Chapter 2: Steady-state kinetics. Chapter 3: Enzyme inhibition. Chapter 4: Effect of pH, temperature, viscosity and other experimental factors. Chapter 5: Reactions of two substrates. Chapter 6: Transient-state kinetics. Chapter 7: Cooperativity and allosteric interactions. Chapter 8: Enzyme inactivators. Chapter 9: Enzyme cofactors. Chapter 10: Mechanism of chymotrypsin. Chapter 11: Basic catalytic principles. Chapter 12: Regulation of catalytic activity. |
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Learning outcomes of the course :
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| The aim of the course is to make students familiar with both enzyme mechanisms and fundamentals of enzyme kinetics. |
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Prerequisites and co-requisites/ Recommended optional programme components :
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| Courses on "Chemistry of biological macromolecules" (BAC3 Biology) or "Biochemistry" (BAC3 Chemistry), which include an introduction to enzyme catalysis (chapters 1-3). |
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Planned learning activities and teaching methods :
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| Most lectures are given using the blackboard and (hopefuly) white chalk. |
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Mode of delivery (face-to-face ; distance-learning) :
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| face-to-face only |
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Recommended or required readings :
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| Lecture notes will be available following the lectures.
Reference book: A. Cornish-Bowden, Fundamentals of enzyme kinetics, fourth edition, Wiley-Blackwell, 2012 |
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Assessment methods and criteria :
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| Oral exam |
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Work placement(s) :
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Organizational remarks :
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| Same schedule as for BIOC0719-1, planned as decided by the professor and students |
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Contacts :
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| Professor André Matagne, PhD, Enzymology and Protein Folding, Centre for Protein Engineering, Life Sciences Department, Institut de Chimie B6c (room 3/1), Allée de la Chimie, 3, University of Liège, B4000 Liège (Sart-Tilman), Tel.: +32 (0)4 3663419, Fax: +32 (0)4 3663396, Email: amatagne@ulg.ac.be |
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