University of Liege | Version française
Academic year 2014-2015Value date : 12/05/2015
BIOC0320-6  General biochemistry

Duration :  25h Th, 10h Pr
Number of credits :  
Bachelor in biomedical sciences, 2nd year4
Bachelor in dental sciences, 2nd year5
Bachelor in pharmaceutical sciences, 2nd year4
Lecturer :  Lucien Bettendorff
Language(s) of instruction :  
French language
Organisation and examination :  
Teaching in the first semester, review in January
Course contents :  
The aim of this course is to bring about an overview of the chemical reactions going in living cells. The program is divided in four parts :
1. molecular constituants of living cells, including proteins and nucleic acids
2. The biochemical reactions: energetics, kinetics and mechanisms
3. The metabolism
4. Storage and transfer of information
Learning outcomes of the course :  
At the end of this course, the students should be able:
1. To recognize the main molecular components of living organisms and their characteristics
2. To understand the basic chemical reactions occurring in living cells, their bioenergetics, the importance of enzymes that catalyze these reactions as wells as the required cofactors.
3. To follow the courses of humain and pathological biochemistry.
4. To give an overview of the techniques used in biomedical laboratories and to understand their principles.
5. To discern established facts from hypotheses and critically examine published literature in the field of general biochemistry.
Prerequisites and co-requisites/ Recommended optional programme components :  
General biology, cytology, chemistry and physics
Planned learning activities and teaching methods :  
Lectures Program and schedule are detailed in the Vade-mecum.  The material will be dispensed through lectures. The active participation of the students is encouraged. During the lectures, the topics will be illustrated through examples, learning strategies and exercices to allow a better understanding of the course.
Practical works Program and schedule detailed in the Vade-mecum. The participation is compulsary.
Two sessions are organized during the six-month period and which relate to the techniques of handling of proteins: chromatography, proteins quantification, enzymatic activity measurement and electrophoresis
Mode of delivery (face-to-face ; distance-learning) :  
The slideshows, complete course notes and knowledge tests are accessible via eCampus.
The students are encouraged to ask questions before and after the lectures and during the breaks.
Recommended or required readings :  
Students can access complete course notes through the e-campus website along with all supporting material (slide shows...). The slide shows presented during the course will be available through e-campus a couple of days before the course if possible. Recommended reading: Principles of Biochemistry, 4th edition, 2012 Donald Voet, Judith G. Voet, Charlotte W. Pratt. Singularités: Jalons sur ses Chemins se la Vie, Christian de Duve (2011)
Assessment methods and criteria :  
Written examination on material seen during the lectures and practical works will be organized according to the general program of the studies. Specific questions pertaining to the practical works count for 15% of the total.
Work placement(s) :  
Organizational remarks :  
The absence at a practical session should be notified to Ms Sabrina DeIuliis (Sabrina.DeIuliis@ulg.ac.be) as soon as possible and accompanied by a medical certificate.
Contacts :  
Professor Lucien Bettendorff, Research Director F.R.S.-FNRS
GIGA-Neurosciences, GIGA-Research,
Tour de Pharmacie (B36), level 1 L.Bettendorff@ulg.ac.be
Tel.: 04 366 5967
Assistents : Laurence Delacroix (ldelacroix@ulg.ac.be), Christel Pequeux (C.Pequeux@ulg.ac.be) and Sabine Wislet (S.Wislet@ulg.ac.be).
Secretary : Sabrina DeIuliis (04 366 3538)(Sabrina.DeIuliis@ulg.ac.be).

Items online :  
Course notes and slideshows
Complet course notes and the slideshows presented during the course are available through eCampus.



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