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| BIOC0002-1 | Biochemistry
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| Duration : | 30h Th, 30h Pr |
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| Number of credits : |
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| Lecturer : | Paulette Charlier |
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Language(s) of instruction :
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| French language |
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Organisation and examination :
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| Teaching in the second semester |
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Course contents :
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| Introduction to the chemistry of living organisms: structural and dynamic aspects. |
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Learning outcomes of the course :
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| General introduction to the properties of living matter at the molecular level.
1. Organic chemistry
2. Life strategy. The living cell.
3. Conservation and use of the genetic information. DNA, RNA and protein synthesis. Mutations, heredity and genetic engineering
4. Protein structure.
5. Biological macromolecules structure determianation by Cristallography.
6. The functions of proteins.
7. Energy cycle. Energy and metabolism: glycolysis and photosynthesis. |
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Prerequisites and co-requisites/ Recommended optional programme components :
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| General chemistry.
Chemical thermodynamics. |
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Planned learning activities and teaching methods :
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| - Exercises : organic chemistry applied to living matter
- Tutorials dedicated to the Pymol software use: obseravtion and analysis of biological macromolecules structures. Courses illustration. Use of PDB database.
- Solving of a protein structure in silico on the basis of X-ray diffraction data. |
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Mode of delivery (face-to-face ; distance-learning) :
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| 15- 4hr periods each comprising 2 hrs of theory and 2hrs of practicals |
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Recommended or required readings :
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| The PowerPoint presentations of the theoretical course will be available on CD as well as the notes of practical works.
Books recommended:
- "Biochimie générale"
Auteur : Jacques-Henry WEIL
Editeur : DUNOD
Collection : Science sup Année: 07/2009 (11ème édition)
- "Crystallography made hook clear: With guide for users for macromolecular models." Scale Rhodos, Academic Press 2000
- "Introduction to Protein Structure" Carl Branden and John Tooze, Garland Publishing 1999
CD roms:
- PS ² and Kinemage Supplement to "Introduction to Protein Structure" Carl Branden and
John Tooze, Garland Publishing 1999 |
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Assessment methods and criteria :
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| Written exam |
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Work placement(s) :
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Organizational remarks :
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| 15 - 4 hrs periodes with 2 hrs of theoretical course followed by 2 hrs of TP. TP is organized at building B37, room -1/45... |
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Contacts :
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| Paulette Charlier, PhD, Chargé de Cours
Cristallographie des macromolécules biologiques, Centre d'Ingénierie des Protéines, Département des Sciences de la Vie, Université de Liège, Institut de Physique, B5a, B-4000 Liège, Belgium
Tel: +32 (0)4 366 36 19
Fax: +32 (0)4 366 49 54
E-mail : Paulette.Charlier@ulg.ac.be
http://www.cip.ulg.ac.be/ |
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