 | | |
| BIOC0001-1 | Genetics, molecular biology and chemistry of biological macromolecules
|
|
| Duration : | 30h Th, 30h Pr |
|
| Number of credits : |
|
|
| Lecturer : | Jacques Dommes, Moreno Galleni |
|
| Coordinator : | Moreno Galleni |
|
Language(s) of instruction :
|
| French language |
|
Organisation and examination :
|
| Teaching in the second semester |
|
Course contents :
|
| 1. Transcription
2. RNA splicing
3. Translation
4. The genetic code
5. Transcriptionnal regulation in Eukaryotes
6. Regulatory RNA
7. Interactions and bounds
8. Organisation of the polypeptide chain
9. Stabilisation and folding of the polypeptide chain
10. Structure-activity relationship
11. Deanturation, inactivation and stability of proteins
12. Determination of protein concentration
13. Analyse of the amino acid sequence of a polypeptide chain
14. Introduction to protein purification
15. Electrophoresis |
|
Learning outcomes of the course :
|
| The first scope of the lectures is to introduce the theoretical and practical bases of the molecular gentic and biology. The second sope will be to improve the student knowledge in advanced biochemistry. The major aim of the course will be to help students for the comprehension of other lectures of the master in ecology and biology of the organism and for the master in biochemistry, molecular and cellular biology. |
|
Prerequisites and co-requisites/ Recommended optional programme components :
|
| Introduction to genetic (BAC2 in biological sciences)
Introduction to Biochemistry and thermodynamic of biological systems. (BAC2 in biologicals sciences) |
|
Planned learning activities and teaching methods :
|
| The pratical courses will be organised on Mondays and Thursdays during the weeks 7 to 10 of the second semester. They consist in problem-based learning activities concerning molecular genetics. They also include practical activities on protein biochemistry |
|
Mode of delivery (face-to-face ; distance-learning) :
|
| Molecular genetics and molecular biology (Prof. J. Dommes) : Mondays and Wednesdays (10:30-12:30) of weeks 9 - 14 of first semester.
Chemistry of macromolecules (Prof. M. Galleni) : Mondays and Thursdays of weeks 1 - 7 during second semester. |
|
Recommended or required readings :
|
| Genetics and molecular biology :
- Molecular Biology of the Gene, VIth edition, J.D. Watson, T.A. Baker, S.P. Bell, A. Gann, M. Levine, R. Losick, Pearson, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York, USA, ISBN 0-321-50781-9
- Powerpoint presentations can be downloaded from MyULg (eCampus).
Partim chemistry of proteins
Power Point presentation + Syllabus |
|
Assessment methods and criteria :
|
| Report and/or test on practical courses.
Written examination on theory.
A minimal note of 8/20 will be requested for the two parts of the course. |
|
Work placement(s) :
|
| |
|
Organizational remarks :
|
| References
- Biologie Moléculaire du Gène, 6ème édition, J.D. Watson, T.A. Baker, S.P. Bell, A. Gann, M. Levine, R. Losick, Pearson Education France, Paris, ISBN 978-2-7440-7348-9.
- Proteins: structures and molecular properties, T.E. Creighton, publié par WH Freeman and Company, New York, USA, ISBN 0-7167-7030-X |
|
Contacts :
|
| - J. Dommes, Prof. Ordinaire, e-mail J.Dommes@ulg.ac.be 04/366.38.99
- M. Galleni, Chargé de cours, e-mail mgalleni@ulg.ac.be 04/366.35.49
- M.-F. Versali, assistante, e-mail mfversali@ulg.ac.be(carole.gauthier@ulg.ac.be 04/366.38.74
)
- G. Feller, chef de travaux, e-mail g.feller@ulg.ac.be 04/366.33.43 |
|
|
| Items online : |
|
| eCampus |
| Powerpoint presentations and other materials available on eCampus. |
|
|
