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| BICP2211-2 | University program - Seminars on medical chemistry, 2nd year - Seminars on microbiology and infectiology, 2nd year - Seminars on hematology, 2nd year - Seminars on medicamentous toxicology, 2nd year - Blood group serology, 2nd year - Biostatistics II, 2nd year - Multivariate statistical analysis, 2nd year - Study of the human genome in normal and pathological methods of molecular biology, 2nd year - Quality insurance, 2nd year
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| Duration : | Seminars on medical chemistry, 2nd year : 25h Th, 120h SEM Seminars on microbiology and infectiology, 2nd year : 25h Th, 120h SEM Seminars on hematology, 2nd year : 25h Th, 120h SEM Seminars on medicamentous toxicology, 2nd year : 15h Th, 120h SEM Blood group serology, 2nd year : 15h Th, 90h Pr Biostatistics II, 2nd year : 15h Th, 15h Pr Multivariate statistical analysis, 2nd year : 10h Th, 10h Pr Study of the human genome in normal and pathological methods of molecular biology, 2nd year : 10h Th, 10h Pr Quality insurance, 2nd year : 10h Th, 10h Pr
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| Number of credits : |
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| Lecturer : | Seminars on medical chemistry, 2nd year : Etienne Cavalier
Seminars on microbiology and infectiology, 2nd year : Marie-Pierre Hayette, Pierrette Melin
Seminars on hematology, 2nd year : André Gothot
Seminars on medicamentous toxicology, 2nd year : Corinne Charlier
Blood group serology, 2nd year : Christiane Gérard
Biostatistics II, 2nd year : N...
Multivariate statistical analysis, 2nd year : N...
Study of the human genome in normal and pathological methods of molecular biology, 2nd year : N...
Quality insurance, 2nd year : Etienne Cavalier
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| Coordinator : | N... |
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Language(s) of instruction :
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| French language |
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Course contents :
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 |  | Seminars on microbiology and infectiology, 2nd year |

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 | En construction |
 |  | Seminars on hematology, 2nd year |

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 | Methods used for the diagnosis of hematology diseases in the clinical laboratory. |
 |  | Seminars on medicamentous toxicology, 2nd year |

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 | Specific cursus on chromatographic methods in a clinical, forensic and environmental toxicology department.
The students will stay for a 2 - 3 monthes in the lab and participate to technical validations, protocol signatures, etc.... |
 |  | Biostatistics II, 2nd year |

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 | This course is the second part of the teaching of Biostatistics at the Faculty of Medicine. It addresses mre advanced statistical methods, such as regression, one-way and two-way analysis of variance (ANOVA), contingency tables and non-parametric statistical techniques.
Each lesson consists of a theoretical exposition of the method followed by a session of practical applications, where the student will get used to solve statistical problems encountered in daily practice. |
 |  | Multivariate statistical analysis, 2nd year |

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 | The course is a general introduction to the descriptive methods and tests used in multivariate statistics, i.e. the study of several variables simultaneously. The course entails the following chapters:
- Short review of matrix calculus
- Graphical display of multivariate data
- Mean vector and dispersion matrix
- Principal component analysis
- Multiple regression and correlation
- Logistic and ordinal regressions
- Survival curves and Cox regression
- Discriminant analysis |
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Learning outcomes of the course :
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 |  | Seminars on microbiology and infectiology, 2nd year |

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 | En construction |
 |  | Seminars on hematology, 2nd year |

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 | 1. Hematology analyzers: instrumentation, detection principles, validation and quality assurance.
2. Immunophenotyping: numeration of lymphocyte sub-populations, numeration of hematopoietic progenitor cells, phenotyping of hematological malignancies. Theory and practical cases.
3. Hemostasis: testing methods, validation and quality assurance of coagulation assays. Monitoring of anticoagulant treatment. Point-of-care testing. Practical cases. |
 |  | Biostatistics II, 2nd year |

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 | The course is intended to improve and enhance the use of biostatistics in health sciences, by insisting on statistical reasoning and problem solving rather than on the mathematics and the complexity of formula. Students should be able to carry out an in-depth statistical analysis of a dataset resulting from an experiment or a survey, in particular with respect to the thesis they will prepare later on in their cursus. |
 |  | Multivariate statistical analysis, 2nd year |

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 | The course is an introduction to the methods of multivariate data analysis. At the end of the course, the sudent should be capable of defining a multivariate problem, analysing the data and interpreting the results. He/she should also be able to understand the use of multivariate methods in the scientific literature. |
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Prerequisites and co-requisites/ Recommended optional programme components :
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 | First-year course |
 |  | Seminars on hematology, 2nd year |

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 | General Hematology. |
 |  | Biostatistics II, 2nd year |

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 | Students should have received the course "Biostatistics I" or some equivalent statistical course. |
 |  | Multivariate statistical analysis, 2nd year |

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 | A good knowledge of univarite statistical methods. |
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Planned learning activities and teaching methods :
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 | Interpretation of clinical cases and comments upon scientific papers
Ex-cathedra courses (specific topics) |
 |  | Seminars on hematology, 2nd year |

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 | Ex cathedra lessons. Discussion of clinical cases. |
 |  | Biostatistics II, 2nd year |

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 | Total: 15 hours
In statistics, practice is most important. Students are therefore requested to attend the practicals. These will be scored and taken into account in the final score of the exam.
Practicals will start on Thursday 8 November 2012 at the Mathematic Institute, usually from 16h30 to 18h30. The last session will be on 13 December 2012.
Please take with you your lecture notes, exercise book, pocket calculator and a pad |
 |  | Multivariate statistical analysis, 2nd year |

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 | The practical sessions consist in analysing mulltivariate datasets by means of the software package Statistica. |
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Mode of delivery (face-to-face ; distance-learning) :
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 | Interpretation of clinical cases (Tutorial groups)
Ex-cathedra short courses on specific topics
Review of scientific papers |
 |  | Seminars on hematology, 2nd year |

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 | Face-to-face lessons. |
 |  | Biostatistics II, 2nd year |

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 | The course will start on Thursday 8 November 2012 at 14h00 at the Auditorium 01 of the Mathematic Institute (Bldg B37, Pkg P32). In general, the course lasts until 16h30 with 10-15 break. The last course will be on 13 December 2012. |
 |  | Multivariate statistical analysis, 2nd year |

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 | Each course consists of 1h30 of theory and 1h of exercises with Statistica. One lecture will be dedicated to Statistica (the corresponding manual has also to be acquired for 10 EUR). The homeworks can be completed at home by the student. |
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Recommended or required readings :
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 |  | Seminars on microbiology and infectiology, 2nd year |

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 | Lippincott's illustrated reviews-Microbiology 2d edition-
R. Harvey and P. Champe Ed. |
 |  | Biostatistics II, 2nd year |

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 | Students will have to buy the lecture notes "Biostatistics, A. Albert, edition 2012" at Point de Vue shop near the large lecture halls at the cost of 15 EUR. This book contains the course material as well the main statistical tables. It will be used during exercise sessions and at the final examination. Finally, it can be used as a reference book in biostatistics in subsequent years.
NB. Students who bought the Biostatistics lecture notes in 1.Bachelor year can use it!
Textbook
D.G. Altman. Practical statistics for medical research. Chapman & Hall, London, 2000. |
 |  | Multivariate statistical analysis, 2nd year |

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 | Students will have to buy the lecture notes "Multivariate statistical analysis", A. Albert, edition 2011" at Editions de l'Université de Liège for 15 EUR. This book contains the course material as well the main statistical tables. It will be used during exercise sessions and at the final examination. Finally, it can be used as a reference book in multivariate statistics in subsequent years, in particular for the final project.
Textbooks are:
- Multivariate statistical methods. D. Morrison, Mc Graw-Hill, Auckland, 1986
- Introduction to multivariate analysis. C. Chatfield et A.J. Collins, Chapman and Hall. ed, London, 1980 |
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Assessment methods and criteria :
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 |  | Seminars on hematology, 2nd year |

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 | Oral exam after written preparation. Open questions. |
 |  | Biostatistics II, 2nd year |

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 | A written test will take place in January. Any score of 10 or more will be considered as a success, exempting the student from the examination in June or September. All exams are written exams and students can used their lectures notes or any other documents. Exams are scored 0-20. |
 |  | Multivariate statistical analysis, 2nd year |

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 | Written examination. |
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Work placement(s) :
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 |  | Seminars on hematology, 2nd year |

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 | Opportunity for master's thesis in the laboratory on the development of clinical assays and their interpretation. |
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Organizational remarks :
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 |  | Multivariate statistical analysis, 2nd year |

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 | The course will normally take place on Wednesday afternoon of the fisrt quadrimester in the auditoria of the University hospital (CHU). Please make sure to chek the name of lecture room before the course starts because it could change from one lecture to another. |
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Contacts :
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 |  | Seminars on microbiology and infectiology, 2nd year |

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 | Department of Medical microbiology
Tel. 04.366.24.39
Lecturers:
Prof. Pierrette Melin
Pierrette.Melin@chu.ulg.ac.be
Prof. Marie-Pierre Hayette
mphayette@chu.ulg.ac.be |
 |  | Seminars on hematology, 2nd year |

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 | Laboratory and Immuno-Hematology Department.
CHU Liège, 1 avenue de l'hopital Sart Tilman B35, B-4000 Liège. Building 2, 6th floor, room 19.
Secretariat: Mrs C. Henet: 04/366 75 36; courriel: hematobio@chu.ulg.ac.be |
 |  | Seminars on medicamentous toxicology, 2nd year |

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 | Prof. Corinne CHARLIER
Service de toxicologie clinique, médicolégale, de l'environnement et en entreprise
Bloc central +3 porte 166 CHU
Tél secrétariat 04/3667683 (B.Cornet)Toxclimedileg@chu.ulg.ac.be
Assistants : Raphaël DENOOZ, Virginie MISTRETTA |
 |  | Biostatistics II, 2nd year |

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 | Lecturer
Adelin ALBERT (Professeur ordinaire), Département des Sciences de la Santé Publique (DSSP)- Informatique Médicale et Biostatistique, CHU Sart Tilman (B35), 4000 Liège.
Tél: 04-366.25.91/90 - Fax: 04-366.25.96 Email: aalbert@ulg.ac.be
Secretary
Mrs Anna MARCHETTA, Département des Sciences de la Santé Publique (DSSP)- Informatique Médicale et Biostatistique (IMBS), CHU Sart Tilman (B35), 4000 Liège.
Tél: 04-366.25.90 - Fax: 04-366.25.96
Email: imbs@ulg.ac.be
Assistants
Laurence SEIDEL-VERMEERSCH (coordination)
Tél: 04-366.25.95 - Email: Laurence.Seidel@ulg.ac.be
Anne-Françoise DONNEAU
Tél: 04-366.47.90 - Email: afdonneau@ulg.ac.be
Nadia DARDENNE
Tél: 04-366.33.40- Email: ndardenne@ulg.ac.be |
 |  | Multivariate statistical analysis, 2nd year |

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 | Lecturer
Adelin ALBERT (Professeur ordinaire), Département des Sciences de la Santé Publique (DSSP)- Informatique Médicale et Biostatistique, CHU Sart Tilman (B35), 4000 Liège. Tél: 04-366.25.91/90 - Fax: 04-366.25.96 Email: aalbert@ulg.ac.be
Secretary
Anna MARCHETTA, Département des Sciences de la Santé Publique (DSSP)- Informatique Médicale et Biostatistique (IMBS), CHU Sart Tilman (B35), 4000 Liège. Tél: 04-366.25.90 - Fax: 04-366.25.96 Email: imbs@ulg.ac.be
Assistant
Anne-Françoise DONNEAU Tél: 04-366.47.90 - Email: afdonneau@ulg.ac.be |
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