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| ANIM0004-4 | Microbial biochemistry and physiology
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| Duration : | 10h Th, 12h Pr |
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| Number of credits : |
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| Lecturer : | Micheline Vandenbol |
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Language(s) of instruction :
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| French language |
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Organisation and examination :
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| Teaching in the second semester |
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Course contents :
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| - Mating in yeast as model organism (sexual reproduction), physiological and molecular description, signal transmission, synthesis and maturation of pheromones ;
- Control of cell division cycle in yeast, cyclins, control of genome integrity and stability ;
- Isolation of ts mutants (temperature-sensitive mutants) and cdc mutants (cell division cycle) in microorganisms;
- Film in english language about the idenficiation of genes that control cell division and about the conservation of regulation process in Eukaryotes;
- Diversity of antimicrobial peptides from bacteria and description of their mechanisms of action;
- Description of some microbial metabolism (nitrogen and phosphate);
- Practical works: methods to measure different parameters of microbial metabolism. |
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Learning outcomes of the course :
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| - Overview of different biochemical and physiological mechanisms from different microbial cellular processes (intracellular transduction, cell division cycle control, nitrogen and phosphate metabolism) ;
- Overview of specialized methods developed to study the microbial metabolism.
After completing the course, the student is expected
- to understand the different aspects of the microbial metabolism and physiology
- to practice the appropriate techniques to study a particular metabolism. |
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Prerequisites and co-requisites/ Recommended optional programme components :
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| BIOL2013 - General microbiology
BIOL2015 - Molecular biology |
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Planned learning activities and teaching methods :
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| PowerPoint available on MyULg. |
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Mode of delivery (face-to-face ; distance-learning) :
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| Lectures : 14h
Practical Works : 10h (obligatory) |
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Recommended or required readings :
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| - Microbiology (Prescott et al.), 2011, 8th edition, McGram-Hill Pub., London, 1088 pages + appendixes
- La levure (P. Thuriaux), 2004, Ed Belin, 282 pages
- The metabolism of Saccharomyces cerevisiae, 2004, Ed J.R. Dickinson, M. Schweizer
- Biologie moléculaire de la cellule (Lodish et al.), 2005, Ed. de Boeck
- Publications from recent literature. |
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Assessment methods and criteria :
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| Written examination (100%) |
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Work placement(s) :
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Organizational remarks :
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Contacts :
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| Vandenbol Micheline (Professeur ordinaire)
Microbiologie et Génomique
081/622353
m.vandenbol@ulg.ac.be |
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