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| CHIM9239-2 | Biological molecules chemistry
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| Duration : | 48h Th |
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| Number of credits : |
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| Lecturer : | Aurore Richel, Bernard Wathelet |
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| Coordinator : | Bernard Wathelet |
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Language(s) of instruction :
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| French language |
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Organisation and examination :
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| Teaching in the second semester |
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Course contents :
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| Aurore Richel :
Carbohydrates : classification of carbohydrates, principal sugars and nomenclature, structure and conformation, chemical reactivity and physical properties, polysaccharides, applications.
Lipids : nomenclature, chemical structure and physico-chemical properties, glycerides, unsaponifiable, application domains.
Bernard Wathelet :
Amino acids, peptides and proteins.
Structure and principal properties.
Exemple of protein structures (alpha-keratin, fibroïn, collagen, elastin).
Protein denaturation mechanism and practical importance.
Amino acids, peptides and proteins :
Analysis, sequence, conformation, peptide synthesis, interactions, modifications, purification.
Structure activitiy of proteins.
Biomolecules analysis and purification methods.
Precipitation, Partition, Ion exchange, Chromatography, Electrophoresis |
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Learning outcomes of the course :
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| To give basic knowledge in organic chemistry of natural molecules.
To draw molecular and structural properties of biomolecules.Present analysis and purification methods for biomolecules.
After completing the course the student is expected to be able to give back the basic knowledge of the three main groups of compounds from biological origin : protein, lipids and glucids, to demonstrate the convergence points with the cursus in organic chemistry and to point out the first applications of the teached topics.Understand the different principles of bio-molecules separation and be able to choose the right principle in function of the molecules to separate
Understand the ionization phenomenon and predict the possible effect on association, biological activity. |
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Prerequisites and co-requisites/ Recommended optional programme components :
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| CHIM9268-1 - General chemistry
CHIM9255-3 - Organic chemistry
CHIM9267-1 Equilibrium chemistry |
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Planned learning activities and teaching methods :
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| Theoretical lectures. |
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Mode of delivery (face-to-face ; distance-learning) :
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| Lectures : 2 fold 24h |
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Recommended or required readings :
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| Lecture-notes |
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Assessment methods and criteria :
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| Written examination (glucide, lipids) : 50%
Oral examination (proteins) : 50% |
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Work placement(s) :
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Organizational remarks :
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Contacts :
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| Richel Aurore (Professor)
Wathelet, Bernard (p.t. Professor)
Université de Liège
Gembloux Agro-Bio Tech
Chimie biologique industrielle
a.richel@ulg.ac.be+32 81 622633
bwathelet@ulg.ac.be+32 81 622225 |
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