University of Liege | Version française
Study programmes 2011-2012Last update : 14/06/2012
MICR0001-1  Complements of microbiology (including bacterial physiology)

Duration :  30h Th
Number of credits :  
Bachelor in biological sciences, 3rd yearSecond semester3
Master in Biological SciencesSecond semester3
Lecturer :  Denis Baurain, Bernard Joris, Jacques Piette
Coordinator :  Jacques Piette
Language(s) of instruction :  
French language
Course contents :  
The virology course will be divided into four chapters:
Chapter 1: Astrovirus & Calcivirus
Chapter 2: Bunyavirus
Chapter 3: The Ebola virus and the filovirus
Chapter 4: Arenavirus
Chapter 5. Immune system activation by viruses

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Owing to their microscopic size, eukaryotic microbes have been discovered only relatively recently -- that is, from the late seventeenth century, which saw the spread of the microscope. Before that, the very idea of single-celled organisms was simply unknown.
Since their discovery, various classifications of Life have tried to accommodate unicellular eukaryotes, always as a monolithic group generally referred to as "protists." With the rise of molecular phylogenetics, evolutionary relationships between eukaryotes (microscopic or not) have been widely challenged only to conclude that protists are an artificial group, out of which emerged independently several lineages of multicellular organisms (e.g., animals, plants, red algae and brown algae).
Building on the knowledge provided by the Microbiology course (part Algology and Mycology) [MICR0711-A] preceding it, this second part of the course of Complements of microbiology aims to deepen the phylogenetic context in which the major lineages of eukaryotic microbes have been presented.
To this end, it will introduce students to historical and methodological aspects of the classification of Life. In particular, it will present concepts of molecular phylogenetics that will be reused at Master's level (BBMC), for example in the course 'Introduction to bioinformatics' [BIOL0845-1].

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The course of bacteriology will give to the students the keys to understand the mechanisms of gene regulation in bacteria, which allow bacteria to adapt to their developement in function of environmental conditions. The following phenomena will be presented and discussed: chemotaxis, quorum sensing, cannibalism and sporulation in Bacillus subtilis. The study of these phenomena will facilitate the acquisition of the concepts of bistability in bacterial populations, regulation by a phospho-relay involving histidine kinases (in parallel, in series or in opposition) and a "AND gate" regulation.
Learning outcomes of the course :  
The virology course will provide to the students supplementary informations on virology. It will also allow to the students to individually search for informations in the litterature and to present them orally.

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After the Algology and Mycology part of the course of Complements of microbiology, students will have a good idea of the diversity and classification of major groups of eukaryotic microbes. They will also be able to explain the methodological principles that have guided the development of the current classification and how it differs from the approaches of the past.

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Objectives of Bacteriology course: understand and explain a mechanism of gene regulation in bacteria.
Prerequisites and co-requisites/ Recommended optional programme components :  
Participation at the first part of the course.
Planned learning activities and teaching methods :  
None
Mode of delivery (face-to-face ; distance-learning) :  
Theoretical course of 90 min.
Recommended or required readings :  
No written notes. The students will receive reference articles, and photocopies of the slides shown during the course. For the Algology and Mycology part, the slides shown during the class will be made available to students through the web portal myULg.
Assessment methods and criteria :  
For virology and algology/mycology, the examination will take place at the same time and in the same way as the first part of the course. For bacteriology, it will be a written exam, taking place at the same time as the exam of algology and mycology.
Contacts :  
Jacques Piette, Directeur de Recherches FNRS et Professeur Adjoint. Laboratoire de Virologie & Immunologie, Institut de Pathologie, Bât. B23, 4000 Liège 1 (Sart Tilman) Tél : 04/366.24.42, Fax : 04/366.24.33, E-mail : jpiette@ulg.ac.be Prof. Denis Baurain Institut de Botanique B22 (P70) denis.baurain@ulg.ac.be Assistant: Dr. Damien Sirjacobs Institut de Botanique B22 (P70) 04/366.38.54 D.Sirjacobs@ulg.ac.be Bernard JORIS Institut de chimie B6a Local 1.50b 04/366 2954 bjoris@ulg.ac.be Fabienne Julémont Secrétariat 04/366 3341

Items online :  
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