IMMU0520-1 : General immunology

University of Liege | Version française

Study programmes 2011-2012

Last update : 14/06/2012

IMMU0520-1

General immunology

Duration :

10h Th

Number of credits :

Bachelor in physiotherapy and readaptation, 2nd year	First semester	2

Bachelor in Motor skills, 2nd year	First semester	2

Lecturer :

Marie‑Paule Defresne

Language(s) of instruction :

French language

Course contents :

Natural and adaptative immunity
Lymphoid organs
MHC, T cell receptor, B cell receptor
Antigen presenting cells
Antibodies and their biological effects
T cell sub-populations and their function
Immunity to bacteria
Anti-viral immunity

Learning outcomes of the course :

The immune system has been developped to protect the organism against infectious pathogens. The defense of the organism depends on "innate" mechanisms and "adaptative" mechanisms. The latter are due to cells, which first recognize pathogens and then proliferate, differentiate into effector cells and develop mechanisms in order to kill pathogens; simultaneously, a "memory" is developped which ensures a better response when the organism is reinfected. Perturbations of these systemes, whatever they are genetic or acquired, would permit to the microorganisms to attack the host and to give pathologies. It is thus important to analyze how the immune system works, how the immune responses are controlled to understand the etiology of some diseases. Immunology is a vast and complex domain, always in progress: this lecture is not exhaustive but will allow to understand how an equilibrium between the host and the pathogens is established and how a rupture of this equilibrium is susceptible to induce diseases.

Prerequisites and co-requisites/ Recommended optional programme components :

microbiology
histology of blood cells
notions of biochemistry

Mode of delivery (face-to-face ; distance-learning) :

Lectures given during the S3 for the students of the 2d candidature in physical training and of the 2d candidature in physiotherapy and readaptation (2 hours per week during 5 weeks).