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| CHIM0331-1 | Analytical chemistry (Part II)
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| Duration : | 15h Th, 20h SEM |
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| Number of credits : |
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| Lecturer : | Philippe Hubert |
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Language(s) of instruction :
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| French language |
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Course contents :
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| To give students the necessary knowledge to use the following methods and skills:
- Preparation of samples: extraction by an immiscible solvent (LLE); solid phase extraction; extraction of solid matrices (mineralisation, extraction by supercritical CO2).
- Capillary electrophoresis: principal characteristics of CE; Principle of electrophoresis, theory, electrophoretic mobility, electro-osmotic flow apparatus.
- Mass spectrometry: General considerations, ionisation techniques, Mass analysers, Mass spectrometry in tandem mode (MS/MS), Coupling of mass spectrometry with chromatography.
- Notions of analytical methodology (Chemometrics): Analysis of data; Experimental planning; Validation. |
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Learning outcomes of the course :
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| To build on the required theoretical concepts with a view to instrumental analysis. To contribute to the general education of future pharmacists on a theoretical level in order to enable them to adopt an analytical approach to work. Teaching is centred on fundamental problems and those encountered in the analysis of medicines (Life cycle of analytical methods). To encourage an analytical and critical approach to work. To deal with the different aspects connected to the experimental planning process and the validation of instrument analysis techniques. (Analytical methodology). |
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Prerequisites and co-requisites/ Recommended optional programme components :
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| Preparatory chemistry for biomedical and pharmaceutical sciences.
Biostatistics.
Physical and mathematical basis for biomedical sciences.
Physical basis of spectroscopic methods of analysis.
Introduction to analytical chemistry (Part I). |
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Planned learning activities and teaching methods :
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| In the context of the life-cycle of analytical procedures, Personal Pedagogical Workshop seminars(PPW in English, APP in French) on medical molecules are organised in order to give students an initial overview of the analytical route of the sample leading up to the result (modes of preparation, selection of measuring methods, suitability of the method retained in relation to the target concentration, (relative calculations). On this occasion they have to carry out personal work which must be orally presented. |
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Mode of delivery (face-to-face ; distance-learning) :
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| Face-to-face.
Theoretical classes take the form of lectures. Casses take place on Monday mornings (8.30am - 10am) during the second term (Q6).
With regard to the seminars (APP), see the grid in the handbook.
The completion of this work (APP) is obligatory and is an integral part of the final mark. |
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Recommended or required readings :
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| Condensed notes and photocopies of Powerpoint presentations are distributed to the students.
General works:
"Chimie analytique"; Skoog, West, Holler (French edition, 7th Ed) Ed. De Boeck University, 2002.
"Analyse Chimique. Méthodes et techniques instrumentales modernes"; Rouessac, Ed. Dunod, 2000.
"Analytical Chemistry", Kellner, Mermet, Otto, Widmer
Ed. Wiley, 1998. |
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Assessment methods and criteria :
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| Theoretical courses:
Written exam on the subjects defined by the teaching and scientific staff: Written exam.
Oral re-sit if marks are insufficient in the written exam (only in the first session).
Seminars (APP):
On this occasion, the students must carry out personal work which will be the subject of a marked oral presentation (In groups of ± 10 students).
The completion and presentation of this work is obligatory. In conformity with article 6 of the general exam rules, any student who has not completed this activity which is an essential part of the teaching may be declared unable to sit the exam. |
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Training(s) :
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| Course possibility.
Student-teachers: possibilities are offered for students interested in teaching analytical chemistry. The tasks consist of the supervision of practical work.
Research: outside the course or exam period (from the end of the 2nd year of the Baccalaureat), motivated students may attend a course in the laboratory (student-researchers). At the end of the course, it is possible to do a PhD in the department. |
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Organizational remarks :
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| There is a forum on "MyULg" (heading: Study-course) where the students can put their questions about the matter. |
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Contacts :
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| Philippe Hubert, Laboratory of Analytical Chemistry, Institute of Pharmacy, CHU, Tour 4, Avenue de l'Hôpital 1, 4000 Liège, Belgium.
Phone. : 04/366.43.16 (15)
Fax : 04/366.43.17
e-mail: ph.hubert@ulg.ac.be
Seminars (APP):
- Cédric Hubert
Phone: +32 4 366.43.19
e-mail : chubert@ulg.ac.be
- Frédéric Lecomte
Phone: +32 4 366.43.19
e-mail : F.Lecomte@ulg.ac.be
- Eric Ziemons
Phone : +32 4 366.43.24
e-mail : eziemons@ulg.ac.be
Secretary:
Valentine Son
Phone. : 04/366.43.16
Fax : 04/366.43.17
e-mail: valentine.son@ulg.ac.be |
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