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| SBIM0481-1 | Molecular and cellular oncology
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| Duration : | 30h Th, 20h SEM |
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| Credits/ECTS : |
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| Holder(s) : | Yvette Habraken, Agnès Noël, Rose Winkler |
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| Language : | French language |
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| Course contents : | Cancer is the result of permanent modifications in the genome of the cell that is the origin point of a tumor. These modifications (mutations) have to do with cancer genes, oncogenes and tumor-suppressive genes. As a result these cells acquire particular capacities that are responsible for a "cancerous phenotype". Normal version of proteins produced by mutated genes are part of the means of communication that control proliferation, apoptosis, migration ... The course will examine modified pathways and their contribution to cancer growth. Beyond the modifications to the genome of cancerous cells themselves, we also observe in cancers disturbances of the relation between cancerous cells and their environment. These matters will be discussed, as well as tumoral angiogenesis, and models allowing us to study cancers in vivo and in vitro. |
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