University of Liege | Version française
	Study programmes 2010-2011 Last update : 11/04/2011
	INFO0430-2   Notions of bioinformatics Duration :   10h Th, 10h Pr Credits/ECTS :   Master in Biomedicine, Research Focus, 1st year First semester 2 Master in Biomedicine, Professional Focus in Quality Assurance, 1st year First semester 2 Master in Biomedicine, Professional Focus in focus in cosmetology, 1st year First semester 2 Master in Biomedicine First semester 2 Holder(s) :   Olivier Peulen Language :   French language Course contents :   The course will define and describe stakes of bioinformatics in XXIst century. Genomic and proteomic databases will be described. Retrieving of sequences in databases will be explained. Some algorithms of exon detection will be exposed. Notions of distance, similarity and homology will be introduced. Dot plots, alignment methods, consensus sequence detection and PCR primer design will be introduced. A chapter will be dedicated to phylogenetics. Content : - Introduction and scenario - Informatic tool - Cell constituants and bioinformatics - Dot-plots - Homology, distance, similarity - Pair alignment - Substitution Matrix - Multiple alignment - FASTA - BLAST - Molecular phylogeny - Genomics and exon detection - Structure prediction - Databases - Genbank - Practical lessons Course objective :   Students might be able to use basic bioinformatic softwares available on WWW and to understand mechanisms involved in this softwares. This understanding might allow them to determine limitations of each procedure. Prerequisites :   Basic knowledge of web. Statistic and Probability Workshops :   Practical use of bioinformatic web ressources : Genbank, Swissprot, PDB, BLAST, primer3, ... Organization :   Lessons take place during the 2nd semester of the first master, 2 h/week for 5 weeks. Written notes :   Syllabus (~150 pages) and a CD with powerpoint files are available. Syllabus can be obtained on My ULg website. Powerpoint files can be obtained on My ULg website. Assessment :   Oral examination Contacts :   Olivier Peulen Metastasis Research Laboratory CHU - Tour de Pathologie B23 Te: 04/366.37.92 E-mail: Olivier.Peulen@ulg.ac.be Remarks :   Textbook : 1) Fundamental concepts of bioinformatics, Dan E. Krane & Michael L. Raymer, Benjamin Cummings Editor (2003) 2) Introduction to Bioinformatics, Arthur M. Lesk, Oxford University Press (2002) Home Search by Faculty Search by teacher Search by course code and title
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