University of Liege | Version française
Study programmes 2010-2011Last update : 11/04/2011
IMMU0520-1  General immunology
Duration :  10h Th
Credits/ECTS :  
Bachelor in physiotherapy and readaptation, 2nd yearFirst semester2
Bachelor in Motor skills, 2nd yearFirst semester2
Holder(s) :  Marie‑Paule Defresne
Language :  French language
Course contents :  
  • Natural and adaptative immunity
  • Lymphoid organs
  • MHC, T cell receptor, B cell receptor
  • Antigen presenting cells
  • Antibodies and their biological effects
  • T cell sub-populations and their function
  • Immunity to bacteria
  • Anti-viral immunity
Course objective :  The immune system has been developped to protect the organism against infectious pathogens. The defense of the organism depends on "innate" mechanisms and "adaptative" mechanisms. The latter are due to cells, which first recognize pathogens and then proliferate, differentiate into effector cells and develop mechanisms in order to kill pathogens; simultaneously, a "memory" is developped which ensures a better response when the organism is reinfected. Perturbations of these systemes, whatever they are genetic or acquired, would permit to the microorganisms to attack the host and to give pathologies. It is thus important to analyze how the immune system works, how the immune responses are controlled to understand the etiology of some diseases. Immunology is a vast and complex domain, always in progress: this lecture is not exhaustive but will allow to understand how an equilibrium between the host and the pathogens is established and how a rupture of this equilibrium is susceptible to induce diseases.
Prerequisites :  
  • microbiology
  • histology of blood cells
  • notions of biochemistry
Organization :  Lectures given during the S3 for the students of the 2d candidature in physical training and of the 2d candidature in physiotherapy and readaptation (2 hours per week during 5 weeks).
Written notes :  
  • notes available at Intercopy
  • slides on line
Assessment :  Written examination
Contacts :  Professeur DEFRESNE
Tél: 04/366.24.03
E-mail: mp.defresne@ulg.ac.be


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