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| GBIO0018-1 | Introduction to tissue engineering
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| Duration : | 30h Th, 30h Pr |
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| Credits/ECTS : |
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| Holder(s) : | Liesbet Geris |
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| Language : | English language |
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| Course contents : | General: Tissue Engineering is an interdisciplinary field that applies the principles of engineering and life sciences toward the development of biological substitutes that restore, maintain, or improve tissue function or a whole. This introductory course aims to address the most important and fundamental topics - biological as well as engineering - of contemporary tissue engineering research.
Detailed content:
* Cells: Stem cells; Morphogenesis, generation of tissue in the embryo; Tissue homeostasis; Cellular signaling
* Scaffolds: The extracellular matrix as a biologic scaffold for tissue engineering; Natural polymers in tissue engineering applications; Degradable polymers for tissue engineering; Degradation of bioceramics; Biocompatibility
* In the lab: Cell source; Cell culture: harvesting, selection, expansion, and differentiation; Cell nutrition; Cryobiology
*Engineering aspects: Scaffold design and fabrication; Controlled release strategies in tissue engineering; Bioreactors for tissue engineering
* Applications: Tissue engineering for skin transplantation; Tissue engineering of cartilage; Tissue engineering of bone; Tissue engineering of the nervous system; Tissue engineering of organ systems
* Ethical issues in tissue engineering |
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| Course objective : | * To provide students with a foundation for engineering tissues based on Nature's own design and optimization criteria.
* To stimulate the students ability to critically review recent published work in the field
* To provide students with the necessary background and vocabulary to communicate with biomedical experts and clinicians. |
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| Prerequisites : | General knowledge of either engineering or biomedical principles (or both) as can be expected from master students. |
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| Workshops : | * Visit to laboratory facilities
* Guest lectures by clinicians
* Peer-to-peer teaching |
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| Organization : | tbd |
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| Written notes : | Reference textbook: Tissue Engineering (Academic Press Series in Biomedical Engineering) by C. van Blitterswijk, P. Thomsen, J. Hubbell, R. Cancedda, J.D. de Bruijn, A. Lindahl, J. Sohier, D.F. Williams. Slides are available. |
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| Assessment : | Students chose (after consultation with the lecturer) a contemporary research article related to an aspect of tissue engineering and will deliver a presentation to the lecturer and their fellow students in which they critically discuss this publication. Also part of the presentation will be a wider discussion on a particular aspect of the publication, building on the course material by means of a literature study. The students will be marked on their presentation in which the following aspects will be of particular importance:
* Critical attitude with respect to the discussed article: do the students try to assess the scientific value of the proposed research
* Thoroughness: did the students gain sufficient insight into the topic?
* Clarity: can the students give their presentation in a comprehensive way?
The presentation will be followed by a group discussion during which the opportunity exists for the other students to ask additional questions. The way in which students are able to handle these questions is also part of the assessment. |
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| Contacts : | Liesbet Geris
tel: 04 366 95 87
liesbet.geris@ulg.ac.be |
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