 |  |
| DEON0002-1 | Questions of ethics - Part I : Animal experimentation - Part II : Human experimentation
 |
 |
| Duration : | Part I : Animal experimentation : 7,5h Th Part II : Human experimentation : 7,5h Th
|
 |
| Credits/ECTS : |
|
 |
| Holder(s) : | Part I : Animal experimentation : Pierre Drion
Part II : Human experimentation : Nicolas Janin
|
 |
| Coordinator : | Pierre Drion |
 |
| Language : | French language |
 |
| Course contents : |
 |  | Part I : Animal experimentation |

 |
 | ... |
 |  | Part II : Human experimentation |

 |
 | ... |
|
 |
| Course objective : |
 |  | Part I : Animal experimentation |

 |
 | Course objective: the course looks at the ethical aspects of animal experimentation and clinical studies in human medicine. The teaching will be centred on students, by reducing the number of lectures and having the students work in groups of two or three, in order to stimulate their thinking through supervised group learning. The aim is to give them the tools to eventually apply to their knowledge (that has either been presented through the course or acquired by themselves) through reflecting on concrete problems, and applying to them a considered approach which responds to those problems.
As far as animal experimentation is involved we will outline the procedures that should be carried out in order to treat laboratory animals properly, according to internationally recognised criteria. Thus, the following will be looked at: moral and ethical concerns, the ethics of pet treatment versus ethics in the framework of animal experimentation. In addition, in vivo research, institutional management committees for animal ethics, the concept of the 'three Rs' in the monitoring of animal health and determining limit points, animal healthcare (animal houses and animal house management, statistics, animal origins, personnel training, personnel and respective responsibilities, environment improvements), the influence of stress on research, the influence of illness on research, antibody production, anesthesia and analgesia, euthanasia, health and personnel security.
We expect students to discover by themselves the main rules and regulations concerning good practice, as well as the role and operating regulations of Ethical Committees. This personal research will be presented to the teachers and other students in the form of a Powerpoint representation. |
 |  | Part II : Human experimentation |

 |
 | Course objective: the course looks at the ethical aspects of animal experimentation and clinical studies in human medicine. The teaching will be centred on students, by reducing the number of lectures and having the students work in groups of two or three, in order to stimulate their thinking through supervised group learning. The aim is to give them the tools to eventually apply to their knowledge (that has either been presented through the course or acquired by themselves) through reflecting on concrete problems, and applying to them a considered approach which responds to those problems.
As far as research on humans is concerned, lecture presentations will look at historical and critical tests, focusing on the influence of the context, in the broadest sense, on the outcome of condemnable practices on human experimentation. A large introduction to the history of eugenics is envisaged, and looks at its consequences for medical practice in the 20th century, some of which we know led to the setting up of the Nuremburg code. At the same time, the history of a large scale scientific fraud will be presented in detail in order to bring to the attention of the students the multiple external influences that can lead a scientist to stray from good practice. The main objective of the lectures is to insist that the students become aware of the great necessity of having a critical mind when it comes to looking at the multiple influences capable of negatively affecting the judgment or behavior of researchers in the field of bio-medics.
We expect students to discover by themselves the main rules and regulations concerning good practice, as well as the role and operating regulations of Ethical Committees. This personal research will be presented to the teachers and other students in the form of a Powerpoint representation. |
|
 |
| Prerequisites : |
 |  | Part I : Animal experimentation |

 |
 | ... |
 |  | Part II : Human experimentation |

 |
 | ... |
|
 |
| Workshops : |
 |  | Part I : Animal experimentation |

 |
 | ... |
 |  | Part II : Human experimentation |

 |
 | ... |
|
 |
| Organization : |
 |  | Part I : Animal experimentation |

 |
 | Organisation: Time: Monday pm
Place : see the course timetable sheets
Student participation: students are required to attend and participate actively (debates)
Particular teaching methods: ex cathedra lectures followed by presentations of work carried out by the students on the basis of a list of subjects drawn up by the teachers, and on which they have worked interactively with the teachers.
Material used by the students. Diverse publications, information drawn from the internet. Presentations are made with the help of Powerpoint files. |
 |  | Part II : Human experimentation |

 |
 | Organisation: Time: Monday from 4.15 to 6.15 p.m. Place : see the course timetable sheets
Student participation: students are required to attend and participate actively (debates)
Particular teaching methods: ex cathedra lectures followed by presentations of work carried out by the students on the basis of a list of subjects drawn up by the teachers, and on which they have worked interactively with the teachers.
Material used by the students. Diverse publications, information drawn from the internet. Presentations are made with the help of Powerpoint files. |
|
 |
| Written notes : |
 |  | Part I : Animal experimentation |

 |
 | All the lecture notes and student presentations will be placed online on a site accessible to ULg students. |
 |  | Part II : Human experimentation |

 |
 | All the lecture notes and student presentations will be placed online on a site accessible to ULg students. |
|
 |
| Assessment : |
 |  | Part I : Animal experimentation |

 |
 | Evaluation of student work: equal weight will be given to oral presentations and written work.
Oral presentations will be graded according to the following criteria: the accuracy and clarity of the content, the originality of the work, the quality of the presentation (the way the problem looked at has been treated, and the quality of the communication) |
 |  | Part II : Human experimentation |

 |
 | Evaluation of student work: equal weight will be given to oral presentations and written work. Oral presentations will be graded according to the following criteria: the accuracy and clarity of the content, the originality of the work, the quality of the presentation (the way the problem looked at has been treated, and the quality of the communication) |
|
 |
| Contacts : |
 |  | Part I : Animal experimentation |

 |
 | Teacher : Pierre Drion (Animal Ethics), CHU, Tour de Pathologie II (B23), 4000 Sart Tilman.
Nicolas Janin (éthique humaine) CHU, Génétique, B35, 4000 Sart Tilman |
 |  | Part II : Human experimentation |

 |
 | Nicolas Janin (Human Ethics), CHU, Génétique, B35, 4000 Sart Tilman |
|
 |

|
|  |