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| CHIM9218-1 | Biospectroscopy and nuclear magnetic resonance applied to biology
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| Duration : | 20h Th, 15h Mon. WS |
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| Credits/ECTS : |
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| Holder(s) : | Christian Damblon |
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| Language : | French language |
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| Course contents : | Biospectroscopy part :
The lecture begins with a short review of the spectral transitions.Afterwards, the following spectroscopic techniques are studied in detail : UV-Visible absorption, linear and circular dichroisms, fluorescence and its polarisation, surface plasmonic resonance. For each technique, the principles, the technical aspects as well as applications to the study of nucleic acids and their interactions with small ligands will be developed. |
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| Course objective : | Biospectroscopy part :
Increase the qualifications of the student concerning the spectroscopic methods available for thestudy of the conformational dynamics of nucleic acids and their interactions with small ligands. |
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| Prerequisites : | Biospectroscopy part :
Chemistry and functional properties of biological macromlecules |
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| Organization : | Biospectroscopy part :
The lecture will be given as a classical form (as interactive as possible) |
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| Written notes : | Biospectroscopy part :
Lecture notes will be available.
reference books :
- Biophysical Chemistry, Cantor and Schimmel
- Principles of Physical Chemistry, Van Holde et al.
- Biological Spectroscopy, Campbell and Dwek
- Physical Biochemistry, Sheehan |
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| Assessment : | Biospectroscopy part :
The assessment will be made by a written examination
The assessment will be validated if a mean quotation higher than or equal to 10/20 is obtained (with the further requirement to get at least 8/20 in each of the two parts of the course) |
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| Contacts : | Biospectroscopy part :
Pierre Colson, Chargé de cours
Office : 3/73B, Chemistry Institute, Sart-Tilman (B6c) 4000-Liège 1
Belgium
Call : 00 32 (0)4/3663406
Fax : 00 32 (0)4/3664577
e-mail : P.Colson@ulg.ac.be |
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