University of Liege | Version française
	Study programmes 2010-2011 Last update : 11/04/2011
	CHIM0678-1   Biochemistry Duration :   30h Th Credits/ECTS :   Bachelor in chemical sciences, 3rd year First semester 3 One-year preliminary programme leading to the Master in Chemical Sciences First semester 3 Holder(s) :   André Matagne Language :   French language Course contents :   Chapter I. Protein structure and function: I.1. Amino acids; I.2. Peptide bond; I.3. Non-covalent interactions; I.4. Secondary structure; I.5. Tertiary and quaternary structures; I.6. Fibrous and globular proteins; I.7. Protein folding. Chapter II. Basic concepts in Enzymology: II.1. General properties of enzymes; II.2. Enzyme kinetics : steady-state - independent binding sites; II.3. Enzyme inhibition; II.4. Catalytic strategies. Chapter III. Biological membranes: III.1. Membrane lipids; III.2. Lipid bilayers; III.3. Membrane proteins; III.4. Structure of membrane proteins. Chapter IV. Nucleic acid and the flow of genetic information: IV.1. Nucleotides; IV.2. DNA structure; IV.3. DNA replication; IV.4. Gene expression. Chapter V. Metabolism: V.1. Glycolysis and gluconeogenesis; V.2. Krebs cycle; V.3 Oxidative phosphorylation; V.4. Photosynthesis Course objective :   The aim of these lectures is to teach students with fundamentals in biochemistry, i.e. 1) the structure of biological (macro)molecules, namely proteins, nucleic acids, lipids and carbohydrates; 2) their organization and function; 3) their metabolism. Emphasis will be given on the application of basic chemical principles in the life sciences. Organization :   30 hours of lectures, given with the help of powerpoint presentations, blackboard and white chalk Written notes :   Lecture notes will be available following the lectures Reference book: Jeremy M. Berg, John L. Tymoczko and Lubert Stryer (2007) Biochemistry (2007), 6th edition, W.H. Freeman and Co., New York. Assessment :   An oral exam will be organized Contacts :   André Matagne, PhD, Professor, Enzymology and Protein Folding, Centre for Protein Engineering, Life Science Department, Institut de Chimie B6c (room 3/1), Allée de la Chimie, 3, University of Liège, B4000 Liège (Sart-Tilman), Tel.: +32 (0)4 3663419, Fax: +32 (0)4 3663396, Email: amatagne@ulg.ac.be, http://www.cip.ulg.ac.be/amatagne.htm (http://www.cip.ulg.ac.be/amatagne.htm" target=_blank eudora="autourl) Home Search by Faculty Search by teacher Search by course code and title
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