University of Liege | Version française
Study programmes 2010-2011Last update : 11/04/2011
BIOL2019-1  Theoretical and physical chemistry applied to structural analysis of biomolecules
Duration :  36h Th, 48h Pr
Credits/ECTS :  
Bachelor in bioengineering, 3rd yearToute l'année7
One-year preliminary programme leading to the Master in BioengineeringToute l'année7
Holder(s) :  Bernard Wathelet
Language :  French language
Course contents :  Description of the ralation between the different spectrometries.
Quantic theory and Schrödinger equation.
Ultraviolet-visible spectrometry.
Infrared and raman spectrometry.
Nuclear magnetic resonance spectrometry (1H, 13C, 2D).
Mass spectrometry.
Coupled techniques.
Course objective :  Understand theoretical basis of spectrometric methods. Apply these techniques to structural analysis of biological molécules.
After completing the course the student is expected to
- understand phenomenons that govern the different spectrometry : ultra-violet, visible, infrared, raman, nuclear magnetic resonance, mass spectrometry.
- read and explain spectra obtained by the different techniques
- apply these techniques on corresponding instruments
- identify a molecule from its different spectra
Prerequisites :  CHIM9237-1 - General chemistry
CHIM9240-1 - Organic chemistry (first part)
Workshops :  Exercise of spectra interpretation with different spectroscopies.
Practice of maldi-tof, LC-MS, IR, GC-MS and NMR techniques.
Organization :  Lectures : 36h
Practical Works : 48h
Written notes :  Lecture-notes
Assessment :  Written examination (Theory 60%, execirces 30%)
Group work (10%)
Contacts :  Wathelet, Bernard (Chargé de cours)
Université de Liège
Gembloux Agro-Bio Tech
Chimie biologique industrielle
+32 81 62 22 25
bwathelet@ulg.ac.be


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