University of Liege | Version française
Study programmes 2010-2011Last update : 11/04/2011
BIOL0803-2  Molecular and cellular physiology
Duration :  40h Th, 20h Pr
Credits/ECTS :  
Master in Biochemistry and Molecular and Cell Biology, Research Focus, 1st yearToute l'année5
Master in Biochemistry and Molecular and Cell Biology, Teaching Focus, 1st yearToute l'année5
Master in Biochemistry and Molecular and Cell Biology, Professional Focus in Industrial Biochemistry, 1st yearToute l'année5
Master in Biological SciencesToute l'année5
Holder(s) :  Patrick Motte, Marc Muller, Marc Thiry
Language :  French language
Course contents :  A) Short introduction :-Structure and organization of biological membranes,-Movement of molecules through the membranes : -i. Simple diffusion -ii. Diffusion through channels -iii. Facilitated transport -iv. Active transport -v. Endo-and exocytosis.

B) Neuronal function : -action potential -role of ion channels - role of active transport - voltage- dependent potassium channel ,sodium channel and calcium channel.

C) Synaptic function : -short recall - role of presynaptic voltage-dependent channels - postsynaptic channels -i. ligand-dependent(fast,slow) -ii. voltage-dependent.

D) Sensory receptors : - recall of the steps of signal transduction - mechanoreceptors - chemoreceptors - electroreceptors - thermoreceptors - photoreceptors - role of ionic transports.

E) Mechanisms of secretion : -recall of basal mechanisms - exocrine, endocrine secretions and neurosecretion - membrane receptors : i. channel receptors, ii. catalytic receptors - water flux : aquaporine.

F)Control of muscle contraction : - contraction-relaxation cycle - receptors in triads - calcium channel - calcium ATPase.

G) Intracellular signalling.

Plant

1. Cell membrane, planticity and synthesis of components

2. Cell signaling

3. The Cell cycle, complement

4. Cell polarity

5.Functional nuclear organization
Course objective :  Study at the cellular and molecular levels of the main processes in animal and plant physiology. When the molecular structure of a protein responsible of a given process is known, the aim of the teaching will be to link this process with the molecular mechanism of the protein.
Prerequisites :  Physiology, biology
Organization :  90 min lesson during 1st and 2d semesters
Written notes :  The powerpoint of every lessons is provided
Assessment :  Examination details will be defined at the beginning of the academic year. A single examination will be organized for both teachers.
Contacts :  P. MOTTE Laboratory of Functional genomics and plant molecular imaging Institut de Botanique, Bât B22, Bld du Rectorat 27, 4000 Liège (Sart Tilman). Tél.: 04/3663810 - Fax: 04/3662960 - Courriel: Patrick.Motte@ulg.ac.be


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