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| BIOC0719-2 | Enzymology
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| Duration : | 15h Th, 25h Pr |
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| Holder(s) : | André Matagne |
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| Language : | French language |
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| Course contents : | Chapter 1: General properties of enzymes. Chapter 2: Steady-state kinetics. Chapter 3: Enzyme inhibition. Chapter 4: Effect of pH, temperature, viscosity and other experimental factors. Chapter 5: Reactions of two substrates. Chapter 6: Transient-state kinetics. Chapter 7: Cooperativity and allosteric interactions. Chapter 8: Enzyme inactivators. Chapter 9: Enzyme cofactors. Chapter 10: Mechanism of chymotrypsin. Chapter 11: Basic catalytic principles. Chapter 12: Regulation of catalytic activity. |
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| Course objective : | The aim of the course is to make students familiar with enzyme mechanisms and understand enzyme kinetics. |
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| Prerequisites : | Courses on "Chemistry of biological macromolecules" (BAC3 Biology) or "Biochemistry" (BAC3 Chemistry), which include an introduction to enzyme catalysis (chapters 1-3). |
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| Workshops : | Problems tutorials and introduction to the scientific instruments |
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| Organization : | 15 hours of lectures, given with the help of a few transparencies, blackboard and white chalk |
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| Written notes : | Lecture notes will be available following the lectures |
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| Assessment : | Oral or written exam |
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| Contacts : | Professor André Matagne, PhD, Enzymology and Protein Folding, Centre for Protein Engineering, Life Sciences Department, Institut de Chimie B6c (room 3/1), Allée de la Chimie, 3, University of Liège, B4000 Liège (Sart-Tilman), Tel.: +32 (0)4 3663419, Fax: +32 (0)4 3663396, Email: amatagne@ulg.ac.be, http://www.cip.ulg.ac.be/amatagne.htm (http://www.cip.ulg.ac.be/amatagne.htm" target=_blank eudora="autourl) |
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