University of Liege | Version française
Study programmes 2010-2011Last update : 11/04/2011
BIOC0340-1  Pathological biochemistry, including clinical chemistry (Part I)
Duration :  22,5h Th, 12,5h SEM
Credits/ECTS :  
Master in Pharmacy, Research Focus, 1st yearFirst semester4
Master in Pharmacy, Professional Focus in Creation and Development of medicines - bio-analysis, 1st yearFirst semester4
Master in Pharmacy, Professional Focus in pharmacy practices, advice and follow-up , 1st yearFirst semester4
Holder(s) :  Jean‑Paul Chapelle
Language :  French language
Course contents :  The course is given in two parts (Partim I and Partim II).

Partim I is devoted to the study of the intermediate metabolism and the relations of the body with the outer environnement :
1. Digestion and absorption
2. Energy, intermediate metabolism and nutrition
3. Hydro-electrolytic metabolism and its pathology
4. Acido-basic balance and its pathology

5. Kidney and renal pathology

and with specific information to Clinical Chemistry laboratory :
1. Organization of the laboratory
2. Pre-analytical phase
3. Technical aspects
4. Interpretation of the results.

Six two-hours seminars are proposed on the following topics: organization of the laboratory, immunoassays, drug metabolism, hematology tests, molecular biology and electrophoretic methods.
Course objective :  The objective of the course is the knowledge of the biochemical lesions which cause diseases, that the abnormality comes from an error of biosynthesis is due to gene mutation, or that it results from an acquired disturbance of metabolic regulation. The course must thus lead the student to include/understand the biochemical mechanisms which underlie normal and pathological phenomena . The course will find its prolongation in the practical applications of biochemical diagnosis in the clinical laboratory.
Prerequisites :  Human biochemistry, Elements of general pathology.
Workshops :  Nothing.
Organization :  Course and seminars given to the 1st four-month period.
Written notes :  A. Notes of course and copies of the illustrations
B. Reference works:
Pathological biochemistry, J. Delattre, G. Durand, J.C. Jardillier, Ed. Medicine-Sciences, Flammarion, 2003.
Clinical biology and pharmacotherapy, A. Adam, ED. Edisem - Maloine, 2003.
Assessment :  Written examination.
Contacts :  Prof J.P. CHAPELLE
Dpt of Clinical Chemistry, TSI +5 CHU B35
Sart Tilman, 4000 Liege
Tel : 04/3667684 - Fax 04/3667666

Secretariat: 04/3668819 - 04/3668822

E-mail: JP.Chapelle@chu.ulg.ac.be


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