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| BICP2011-4 | University program - Seminars on medical chemistry, 2nd stage - Seminars on microbiology and infectiology, 2nd year - Seminars on hematology, 2nd year - Seminars on medicamentous toxicology, 2nd year - Elements of Analytical Chemistry, 2nd year - Blood group serology, 2nd year - Biostatistics II, 2nd year - Multivariate statistical analysis - Study of the human genome in normal and pathological methods of molecular biology, 2nd year - Quality insurance, 2nd stage
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| Duration : | Seminars on medical chemistry, 2nd stage : 25h Th, 120h SEM Seminars on microbiology and infectiology, 2nd year : 25h Th, 120h SEM Seminars on hematology, 2nd year : 25h Th, 120h SEM Seminars on medicamentous toxicology, 2nd year : 15h Th, 100h SEM Elements of Analytical Chemistry, 2nd year : 20h Th Blood group serology, 2nd year : 15h Th, 90h Pr Biostatistics II, 2nd year : 15h Th, 15h Pr Multivariate statistical analysis : 10h Th, 10h Pr Study of the human genome in normal and pathological methods of molecular biology, 2nd year : 10h Th, 10h Pr Quality insurance, 2nd stage : 10h Th, 10h Pr
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| Credits/ECTS : |
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| Holder(s) : | Seminars on medical chemistry, 2nd stage : Jean‑Paul Chapelle
Seminars on microbiology and infectiology, 2nd year : Patrick De Mol
Seminars on hematology, 2nd year : André Gothot
Seminars on medicamentous toxicology, 2nd year : Corinne Charlier
Elements of Analytical Chemistry, 2nd year : Philippe Hubert
Blood group serology, 2nd year : N...
Biostatistics II, 2nd year : Adelin Albert
Multivariate statistical analysis : Adelin Albert
Study of the human genome in normal and pathological methods of molecular biology, 2nd year : N...
Quality insurance, 2nd stage : Jean‑Paul Chapelle
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| Coordinator : | Patrick De Mol |
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| Language : | French language |
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| Course contents : |
 |  | Seminars on medicamentous toxicology, 2nd year |

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 | ....... |
 |  | Biostatistics II, 2nd year |

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 | This course is the second part of the teaching of Biostatistics at the Faculty of Medicine. It addresses mre advanced statistical methods, such as regression, one-way and two-way analysis of variance (ANOVA), contingency tables and non-parametric statistical techniques.
Each lesson consists of a theoretical exposition of the method followed by a session of practical applications, where the student will get used to solve statistical problems encountered in daily practice. |
 |  | Multivariate statistical analysis |

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 | The course is a general introduction to the descriptive methods and tests used in multivariate statistics, i.e. the study of several variables simultaneously. The course entails the following chapters:
- Short review of matrix calculus
- Graphical display of multivariate data
- Mean vector and dispersion matrix
- Principal component analysis
- Multiple regression and correlation
- Logistic and ordinal regressions
- Survival curves and Cox regression
- Discriminant analysis |
 |  | Quality insurance, 2nd stage |

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 | Quality assurance systems ; accreditation bodies and audit procedure ; documentation ; quality manual ; standard operating procedures ; quality manager ; technique validation ; internal quality control ; internal audits ; corrective and preventive actions ; complaints ; specific goals in clinical laboratoires. |
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| Course objective : |
 |  | Biostatistics II, 2nd year |

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 | The course is intended to improve and enhance the use of biostatistics in health sciences, by insisting on statistical reasoning and problem solving rather than on the mathematics and the complexity of formula. Students should be able to carry out an in-depth statistical analysis of a dataset resulting from an experiment or a survey, in particular with respect to the thesis they will prepare later on in their cursus. |
 |  | Multivariate statistical analysis |

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 | The course is an introduction to the methods of multivariate data analysis. At the end of the course, the sudent should be capable of defining a multivariate problem, analysing the data and interpreting the results. He/she should also be able to understand the use of multivariate methods in the scientific literature. |
 |  | Quality insurance, 2nd stage |

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 | This course provides informations on quality assurance systems implementation and development in clinical laboratoires, on the ISO 17025 international standard for assay laboratories and on the ISO 15189 international standard, specific to the medical laboratoires. |
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| Prerequisites : |
 |  | Biostatistics II, 2nd year |

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 | Students should have received the course "Biostatistics I" or some equivalent statistical course. |
 |  | Multivariate statistical analysis |

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 | A good knowledge of univarite statistical methods. |
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| Workshops : |
 |  | Biostatistics II, 2nd year |

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 | Total: 15 hours
In statistics, practice is most important. Students are therefore requested to attend the practicals. These will be scored and taken into account in the final score of the exam.
Practicals will start on Thursday 28 October 2010 at the Mathematic Institute, usually from 16h30 to 18h30. The last session will be on 16 December 2010.
Please take with you your lecture notes, exercise book, pocket calculator and a pad |
 |  | Multivariate statistical analysis |

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 | The practical sessions consist in analysing mulltivariate datasets by means of the software package Statistica. |
 |  | Quality insurance, 2nd stage |

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 | Pratical problems in quality management. |
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| Organization : |
 |  | Biostatistics II, 2nd year |

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 | The course will start on Thursday 28 October 2010 at 14h00 at the Auditorium 01 of the Mathematic Institute (Bldg B37, Pkg P32). In general, the course lasts until 16h30 with 10-15 break. The last course will be on 16 December 2010. |
 |  | Multivariate statistical analysis |

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 | Each course consists of 1h30 of theory and 1h of exercises with Statistica. One lecture will be dedicated to Statistica (the corresponding manual has also to be acquired for 10 EUR). The homeworks can be completed at home by the student. |
 |  | Quality insurance, 2nd stage |

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 | This course is given in the first four-month period. |
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| Written notes : |
 |  | Biostatistics II, 2nd year |

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 | Students will have to buy the lecture notes "Biostatistics, A. Albert, edition 2010" at Point de Vue shop near the large lecture halls at the cost of 15 EUR. This book contains the course material as well the main statistical tables. It will be used during exercise sessions and at the final examination. Finally, it can be used as a reference book in biostatistics in subsequent years.
Textbook
D.G. Altman. Practical statistics for medical research. Chapman & Hall, London, 2000. |
 |  | Multivariate statistical analysis |

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 | Students will have to buy the lecture notes "Multivariate statistical analysis", A. Albert, edition 2008" at Pr Albert's office at CHU for 15 EUR. This book contains the course material as well the main statistical tables. It will be used during exercise sessions and at the final examination. Finally, it can be used as a reference book in multivariate statistics in subsequent years, in particular for the final project.
Textbooks are: - Multivariate statistical methods. D. Morrison, Mc Graw-Hill, Auckland, 1986 - Introduction to multivariate analysis. C. Chatfield et A.J. Collins, Chapman and Hall. ed, London, 1980 |
 |  | Quality insurance, 2nd stage |

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 | Documents (international standards and copies of standard operating procedures). |
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| Assessment : |
 |  | Seminars on medicamentous toxicology, 2nd year |

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 | .... |
 |  | Biostatistics II, 2nd year |

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 | A written test will take place in January. Any score of 10 or more will be considered as a success, exempting the student from the examination in June or September. All exams are written exams and students can used their lectures notes or any other documents. Exams are scored 0-20. |
 |  | Multivariate statistical analysis |

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 | Written examination. |
 |  | Quality insurance, 2nd stage |

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 | Written examination. |
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| Contacts : |
 |  | Seminars on medicamentous toxicology, 2nd year |

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 | ..... |
 |  | Biostatistics II, 2nd year |

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 | Lecturer
Adelin ALBERT (Professeur ordinaire), Département des Sciences de la Santé Publique (DSSP)- Informatique Médicale et Biostatistique, CHU Sart Tilman (B35), 4000 Liège.
Tél: 04-366.25.91/90 - Fax: 04-366.25.96 Email: aalbert@ulg.ac.be
Secretary
Mrs Anna MARCHETTA, Département des Sciences de la Santé Publique (DSSP)- Informatique Médicale et Biostatistique (IMBS), CHU Sart Tilman (B35), 4000 Liège.
Tél: 04-366.25.90 - Fax: 04-366.25.96
Email: imbs@ulg.ac.be
Assistants
Laurence SEIDEL-VERMEERSCH (coordination)
Tél: 04-366.25.95 - Email: Laurence.Seidel@ulg.ac.be
Anne-Françoise DONNEAU
Tél: 04-366.47.90 - Email: afdonneau@ulg.ac.be
Nadia DARDENNE
Tél: 04-366.33.40- Email: ndardenne@ulg.ac.be |
 |  | Multivariate statistical analysis |

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 | Lecturer
Adelin ALBERT (Professeur ordinaire), Département des Sciences de la Santé Publique (DSSP)- Informatique Médicale et Biostatistique, CHU Sart Tilman (B35), 4000 Liège. Tél: 04-366.25.91/90 - Fax: 04-366.25.96 Email: aalbert@ulg.ac.be
Secretary
Anna MARCHETTA, Département des Sciences de la Santé Publique (DSSP)- Informatique Médicale et Biostatistique (IMBS), CHU Sart Tilman (B35), 4000 Liège. Tél: 04-366.25.90 - Fax: 04-366.25.96 Email: imbs@ulg.ac.be
Assistant
Anne-Françoise DONNEAU Tél: 04-366.47.90 - Email: afdonneau@ulg.ac.be |
 |  | Quality insurance, 2nd stage |

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 | Prof. J.P. CHAPELLE Dpt.of Clinical Chemistry, TSI +5 CHU B35 Sart Tilman, 4000 Liège Tel : 04/3667684 - Fax 04/3667666 Secrétariat : 04/3668819 - 04/3668822
E-mail : JP.Chapelle@chu.ulg.ac.be |
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| Remarks : |
 |  | Multivariate statistical analysis |

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 | The course will normally take place on Wednesday afternoon in the auditoria of the University hospital (CHU). Please make sure to chek the name of lecture room before the course starts because it could change from one lecture to another. |
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