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| SBIM0470-1 | Systems Neurobiology
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| Duration : | 20h Th |
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| Credits/ECTS : |
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| Holder(s) : | Jacques Balthazart |
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| Language : | Langue française |
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| Course contents : | Systems neurobiology is a multidisciplinary science representing a part of neurosciences in general that studies the functionning of neuronal circuits. This science analyzes the behavior of neurons, as parts of neuronal circuits, which contribute to attaining a common goal or function. This discipline thus studies how neuronal circuits analyze sensory information to organise a perception of the outside world, integrate this information and generate motor outputs. This research is at the interface of various disciplines ranging from cellular or molecular biology to the analysis of higher mental functions such as language, memory and self awareness. This course will summarize the anatomical and functional bases of the different sensory and motor systems and then will integrate and illustrate this knowledge through a more detailed analysis of a few selected systems. |
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| Course objective : | Learn key notions concerning the functionning of sensory, motor and integrative systems in the central nervous system. |
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| Prerequisites : | SBIM0473-1
Functional neuroanatomy of vertebrates - Rachelle Franzen |
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| Organization : | The main topics that will be covered are:
1) Neuronal networks
a) techniques: histology, ICC, ISH, autoradiography, tract tracing, imaging (MRI, fMRI, PET)
b) coding of information by neuronal circuits (intensity, duration, quality)
2) Somato-sensory systems
a) principles for encoding of various stimuli
b) somato-sensitive systems (epicritic sensistivity, pain): anatomy and physiology (in collaboration with Jean Schoenen)
c) sensory organs (vision, audition, olfaction, taste): anatomy and physiology
3) Motor systems
Short summary (will be described in the course of R. Franzen)
4) Autonomous nervous system
a) neuroendocrine and hypophyseal systems
b) autonomic functions: biological clocks, thermoregulation, cardiovascular control, respiration
5) Examples of integration
a) Limbic system: motivation, addiction
b) Sexual behavior: sexual receptivity and control of lordosis in rats
c) Male sexual behavior: integration of external and hormonal stimuli- the role of steroids
d) learned vocalizations: songbirds and humans
d) memory and consciousness: anatomy and physiology |
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| Written notes : | The reference book will be:
Purves D. et al. 2005 Neuroscience.
DeBoeck, Bruxelles
Additional information could be found in:
1) Zigmond, M.J. et al. 1999 Fundamental Neuroscience. Academic Press San Diego
and
2) Longstaff A. 2000. Instant Notes . Neuroscience. Springer Verlag.
The iconography used during the lectures will be made available to the students in the form of Powerpoint files. |
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| Assessment : | A final written exam will be organized based on open questions covering the main concepts of the course. |
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| Contacts : | Dr. Jacques BALTHAZART 04/366 59 70 (jbalthazart@ulg.ac.be) |
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