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| PHYL0120-1 | General physiology
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| Duration : | 30h Th, 10h Pr, 5h SEM |
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| Credits/ECTS : |
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| Holder(s) : | N... |
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| Substitute(s) : | Bernard Rogister |
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| Language : | Langue française |
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| Course contents : | Teacher : B. Rogister, Chargé de Cours
General Physiology, according to the definition given by Claude Bernard, consists of the study of the general properties common to all cells, without distinguishing between type or family. This principally involves the study of the hierarchies and the interactions which govern the functioning of biological systems, and ecosystems in particular, from the molecule to multicellular living organisms. The principles of evolution will necessarily be considered as well. |
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| Course objective : | - To explain how the cell structure is maintained and how the cell can assume a particular function (cell membrane permeability, cellular volume regulation, muscle contraction, transmission of nervous information ...)
- To give a molecular explaination to the phenomens characterizing the living organisms.
- To introduce the complexity of the coordination system regulating the interactions between the different systems of the organism.
- To examin the relationships between particular metabolic pathways and the environmental properties.
- To constitute an introduction to human physiology. |
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| Prerequisites : | Logically enough, first BAC courses, in particular physics, chemistry and biology, make up the prerequisites for the course on physiology.
This course constitutes an introduction to Human Biochemistry, Human Physiology and Pathology. |
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| Workshops : | Two seminaries will be organized in small groups of students, in order to detail some aspects of the theory, describing the experiments which have led to different hypothesis, methodology, results and interpretations. |
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| Organization : | 1. General introduction, homeostasy
2. Physico-chemical basis of internal regulation
3. Ionic channels and excitable membranes
4. Solutes transports
5. Message transduction |
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| Written notes : | Syllabus actualized in 2008 will be available at the beginning of the course. The students will be refered to some internet references.
All the recent books dedicated to General Physiology or Cellular Physiology can, be used. For example :
- Physiologie des Régulations par E. Schoffeniels et G. Moonen, Masson
- Cell Biology, T.D Pollard and W.C. Earnshaw, 2004, Saunders
- Cellular Physiology, M.P. Blaustein, J.P.Y. Kao and D.R. Matteson, 2004, Elsevier Mosby.
- Molecular Cell Biology, Lodish, Berk, Zipursky, Matsudeira, Baltimore and Darnell, 4th edition, Freeman.
- Cell Physiology Sourcebook, a molecular approach. Ed by Nicholas Sperelakis, 3rd edition, 2001, Academic Press. |
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| Assessment : | The exam will consist of multiple choice questions and open questions. Specific question are dedicated to the aspects developped during seminaries. |
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| Contacts : | Adress : Bernard Rogister, Department of biomedical sciences and preclinics / General Biochemistry and Physiology, Human Biochemistry C.H.U. Bât. B36 avenue de l'Hôpital 1 4000 Liège 1 Belgique
Phone : +32 4 3665917 or +32 4 3665918 E-mail : Bernard.Rogister@ulg.ac.be |
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