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| ESHY0126-1 | Ecotoxicology and Environmental Toxicology
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| Duration : | 20h Th, 20h Pr |
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| Credits/ECTS : |
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| Holder(s) : | Corinne Charlier, Célia Joaquim‑Justo |
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| Language : | Langue française |
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| Course contents : | Partim Toxicologie:
First an Introduction about the Historical development of toxicology, several penetration ways of toxics in organisms and relations between dose and answers, and between dose and effects will be done.
Then toxicokinetics of chemical substances and main factors able to modify it will be taught.
Mechanisms of cellular actions of toxics will be briefly discussed and contamination of soil, air and water will be explained.
Partim Ecotoxicologie:
Parameters that determine the fate of pollutants in the biosphere (transport, partition, degradation) and in organisms (accumulation, redistribution, biotransformation, detoxification and elimination) will be presented.
Effects of pollutants on organisms will be reviewed in detail (ecotoxicological testing, dose-response relationships, mechanisms of action on the molecular, cellular, tissular, physiological, organismic and population levels).
Tools available to assess impacts (biomonitoring and biomarquers) will be presented. |
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| Course objective : | Partim Toxicologie:
To improve knowledge in :
A. INTRODUCTION
B. BASIC KNOWLEDGE
1. Penetration ways
2. Different kinds of intoxication
3. Relations dose-answer, and dose-effects
C. TOXICOKINETICS
1. ADME
2. Factors able to modify kinetics
D. TOXICODYNAMICS
E. SOIL, AIR, WATER POLLUTION
Partim Ecotoxicologie:
The objectives for this part of the course are:
-to provide the knowledge that allows understanding of the factors and mechanisms involved in the impact of chemical pollutants on ecosystems
- to present the specificities related to the different types of pollutants and draw awareness on the context that lead to the major contaminations by chemical pollutants;
- to provide an overview of the strategies developed to manage ecotoxicological impacts with focus on problems that are not fully controlled nowadays. |
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| Workshops : | Ecotoxicological tests will be carried out in the laboratory so students become aware of the strengths and limitations of these tests on which risk assessment is largely based. |
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| Organization : | First semester (one lecture attended, by-your-self learning, one question/answer meeting) |
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| Written notes : | Slides will be read on-line and downloaded. Access will be authorized after the introduction lecture |
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| Assessment : | Oral examination (January) |
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| Contacts : | Professeur Corinne CHARLIER
Clinical, Forensic and Environmental Toxicology laboratory
CHU B35
Sart-Tilman, B4000 Liège
Tél. 04/3667683
Fax 04/3668889
e-mail : C.Charlier@chu.ulg.ac.be
Dr. Célia Joaquim-Justo
Bât. B6c, Allée du 6 Août n°15, Sart-Tilman, 4000 Liège
Celia.Joaquim-Justo@ulg.ac.be
Tel : + 32 4 366 51 40 |
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