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| BIOL0113-4 | General preparatory biology for biomedical and dental sciences, including introduction to molecular biology and human anatomy, general embryology and general genetics - General biology preparing to biomedical and dental sciences, including introduction to molecular biology - General Embryology - General Genetics - Introduction to Human Anatomy
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| Duration : | General biology preparing to biomedical and dental sciences, including introduction to molecular biology : 65h Th, 40h Pr, 20h QA Sess. General Embryology : 10h Th General Genetics : 10h Th Introduction to Human Anatomy : 20h Th, 10h QA Sess.
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| Credits/ECTS : |
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| Holder(s) : | General biology preparing to biomedical and dental sciences, including introduction to molecular biology : Vincenzo Castronovo
General Embryology : Jean‑Pierre Schaaps
General Genetics : Vincent Bours
Introduction to Human Anatomy : Pierre Bonnet
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| Substitute(s) : | General biology preparing to biomedical and dental sciences, including introduction to molecular biology : Akeila Bellahcene
General Embryology : / General Genetics : / Introduction to Human Anatomy : /
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| Coordinator : | Vincenzo Castronovo |
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| Language : | Langue française |
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| Course contents : |
 |  | General biology preparing to biomedical and dental sciences, including introduction to molecular biology |

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 | xx |
 |  | General Embryology |

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 | How can a living being develop from a single cell? How do incredibly precise steps follow each other in space and time to form a photoreceptor organ, a lens and muscles able to properly control its sequence as well as structures secreting the fluid for the transmission of light? Where will the left and the right sides, the belly and the back, the head and the tail appear from an apparently unorganized cell mass? Whether cells are free or structured into tissues, they get organized, move and evolve in terms of shape and function following a single rule: close interdependence. Nature needed more than 2 billion years to create what we see today ¿ not by developing endless basic information items (we have only 30,000 genes) but by increasing the number of possible multiple regulations (if there was a coding gene for each iris structure, there would not be enough of them!). The General Embryology course aims at explaining the different steps and ¿ above all ¿ the mechanisms used for building autonomous organisms. |
 |  | General Genetics |

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 | The course is intended for 1st-year students in medicine and dental sciences. It aims at introducing basic genetic concepts while demonstrating prospects in the medical and biological fields. The course presents theoretical bases and describes the human genome, as well as simple and complex genes transmission. It also deals with the essentials of population genetics and focuses on the issue of genetic defects and medical consequences.
Chapter 1. Genes and genome Chapter 2. Gene transmission Chapter 3. Complex gene transmission Chapter 4. Population genetics Chapter 5. Genetic defects |
 |  | Introduction to Human Anatomy |

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 | Introduction
Historical overview - Definition of Anatomy
General considerations
Anatomical studies: dissection, microscopic study, use of informations from medical imaging, use of computer assisted imaging, anatomical tools for description
Sytematic anatomy
-locomotor system -cardiovascular system -respiratory system -digestive system -nervous system -uro-genital and reproductive systems
Introduction to topographic and clinical anatomy |
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| Course objective : |
 |  | General biology preparing to biomedical and dental sciences, including introduction to molecular biology |

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 | xx |
 |  | General Embryology |

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 | Session 1:
- The development of gametes: general principles - Oogenesis - Spermatogenesis
Session 2:
- Fertilization - Segmentation
Session 3:
- Didermic embryos and development of placenta and amniotic membranes - Gastrulation - Definition of inducer tissues
Session 4:
- Three-dimensional embryos - Branchiomery - Systems for specific exchanges with the external world: . Birds . Mammals . Multiple gestation
Session 5:
- Cell bases for morphogenesis - Adhesion or environment-analysis molecules - Development genes |
 |  | General Genetics |

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 | - Defining the organization of genes. Defining intragenic and extragenic DNA. Understanding prokaryotic and eukaryotic genomic structures.
- Understanding the rules for the hereditary transmission of simple genetic characters. Understanding genetic recombination mechanisms.
- Understanding the notion of quantitative trait. Assessing interactions between genes and the environment for the determination of complex traits. Understanding methods for exploring the role of heredity in the determination of complex traits and pathologies.
- Understanding how intra- or interpopulation genetic variations can be observed. Mastering and applying the Hardy-Weinberg law. Mastering and understanding how to modify the Hardy-Weinberg balance. |
 |  | Introduction to Human Anatomy |

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 | The goals of that course are multiple: -first: to give an overview of the general architecture of the human body to allow a good undserstanding of the principal physiological processes -second: to give an integrative view of the anatomy -third: to train the student with the 3D vision of the human body and its components by the use of the descriptive tools (from old tool (as section, schemes...) to niew tools (computer assisted imaging, 3D reconstruction) |
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| Prerequisites : |
 |  | General biology preparing to biomedical and dental sciences, including introduction to molecular biology |

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 | xx |
 |  | Introduction to Human Anatomy |

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 | None |
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| Workshops : |
 |  | General biology preparing to biomedical and dental sciences, including introduction to molecular biology |

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 |  | Introduction to Human Anatomy |

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 | Demonstrations are organized in 5 occurences (10 for medical students). Demonstration will be held in the "Institut of human Anatomy" rue de Pitteurs or will be avalaible on line on the WebCT course. Participation is mendatory for both of them. |
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| Organization : |
 |  | General biology preparing to biomedical and dental sciences, including introduction to molecular biology |

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 | xx |
 |  | General Embryology |

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 | The course is taught in the second term. Schedules and rooms will be published in the vade mecum. |
 |  | General Genetics |

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 | Lecture in French + 1 repetition with exercises 10 hours, 2nd term +1 hour repetition at the end of the term On Fridays from 10:15am to 12:15am. |
 |  | Introduction to Human Anatomy |

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 | Schedul for each section will be published in the "vademecum"
On line ressources are available trough "My Ulg" > "WebCT". >
Slides, demonstrations, discussions and auto-evaluation can be found on that on line course . A special workshop "how to use your on line course" will be organized in october or november.http://www.webct.ulg.ac.be/webct/logon/137759553001 |
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| Written notes : |
 |  | General biology preparing to biomedical and dental sciences, including introduction to molecular biology |

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 | xx |
 |  | General Genetics |

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 | Analyse Génétique Moderne by Griffiths, Gelbart, Miller & Lewontin, De Boeck Université. |
 |  | Introduction to Human Anatomy |

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 | A syllabus is published each year The 2008-2009 version will be available in january including the 3 adapted chapters last year. For the student using the 2007-2008 edtioon of the syllabus, those 3 chapters will be downloadable from the on line course. Schedule of learning objectives will be downloadable.
Reference book: Possession of these books is not essential!!!
1) General anatomy, core text 2) Introduction à l'anatomie (Masson) 3) Clinical anatomy (K.L.Moore) 4) Gray's Anatomy for students. (french version avalaible) |
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| Assessment : |
 |  | General biology preparing to biomedical and dental sciences, including introduction to molecular biology |

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 | xx |
 |  | General Embryology |

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 | Written test during the June biomedical sciences module: open questions, true/false questions and multiple-choice questions. |
 |  | General Genetics |

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 | Within the biology module. Written exam (multiple choice + true/false questions with explanations). |
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| Contacts : |
 |  | General biology preparing to biomedical and dental sciences, including introduction to molecular biology |

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 |  | General Genetics |

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 | Lecturer in charge
Bours Vincent, Professor CHU B35 Phone: 04-3668145 Email: vbours@ulg.ac.be
Secretary
Fertons Marianne
Phone: 04-3668145 Email: genetique.humaine@ulg.ac.be |
 |  | Introduction to Human Anatomy |

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 | Professor:
Professor P.BONNET - Human Anatomy & Urological department CHU Sart Tilman, Bât. B35 (phone.: 04/366.72.52; e-mail: P.Bonnet@chu.ulg.ac.be: for problems not relative to the course, for questions about the anatomy > please use the forum tool on the online course)
Secretaress :
Anatomy : Messieurs G.Dessers et A. Botte : rue de Pitteurs, institut d'anatomie , phone 04 366 51 51(2 et 3)
Mme G. POLAIN - Service d'Urologie - CHU Sart Tilman Bât.B35 (phone: 04/366.72.52) |
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| Remarks : |
 |  | General biology preparing to biomedical and dental sciences, including introduction to molecular biology |

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 | None. |
 |  | Introduction to Human Anatomy |

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 | High speed internet connexion offers the best way to connect to the on line course, especially for the demonstrations based on videos or animations. A multimedia lab with 13 high speed internet connexion computers is accessible for all students int the Institut for Human Anatomy, rue de pitteurs, with colors print facilities. Plesase contact Mr A. Botte, Prosector, for schedulle. Your student's card is required for access to the lab.
Other multimedia lab are avalaible in the university. Wireless ressources are avalaible in most of the classrooms. |
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