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| BIOL0113-3 | General preparatory biology for biomedical and dental sciences, including introduction to molecular biology and human anatomy, general embryology and general genetics - General biology preparing to biomedical and dental sciences, including introduction to molecular biology - General Embryology - General Genetics - Introduction to Human Anatomy
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| Duration : | General biology preparing to biomedical and dental sciences, including introduction to molecular biology : 65h Th, 40h Pr, 20h QA Sess. General Embryology : 10h Th General Genetics : 10h Th Introduction to Human Anatomy : 30h Th, 20h QA Sess.
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| Credits/ECTS : |
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| Holder(s) : | General biology preparing to biomedical and dental sciences, including introduction to molecular biology : Vincenzo Castronovo
General Embryology : Jean‑Pierre Schaaps
General Genetics : Vincent Bours
Introduction to Human Anatomy : Pierre Bonnet
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| Substitute(s) : | General biology preparing to biomedical and dental sciences, including introduction to molecular biology : Akeila Bellahcene
General Embryology : / General Genetics : / Introduction to Human Anatomy : /
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| Coordinator : | Vincenzo Castronovo |
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| Language : | Langue française |
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| Course contents : |
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 |  | General Embryology |

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 | How can a living being develop from a single cell? How do incredibly precise steps follow each other in space and time to form a photoreceptor organ, a lens and muscles able to properly control its sequence as well as structures secreting the fluid for the transmission of light? Where will the left and the right sides, the belly and the back, the head and the tail appear from an apparently unorganized cell mass? Whether cells are free or structured into tissues, they get organized, move and evolve in terms of shape and function following a single rule: close interdependence. Nature needed more than 2 billion years to create what we see today ¿ not by developing endless basic information items (we have only 30,000 genes) but by increasing the number of possible multiple regulations (if there was a coding gene for each iris structure, there would not be enough of them!). The General Embryology course aims at explaining the different steps and ¿ above all ¿ the mechanisms used for building autonomous organisms. |
 |  | General Genetics |

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 | The course is intended for 1st-year students in medicine and dental sciences. It aims at introducing basic genetic concepts while demonstrating prospects in the medical and biological fields. The course presents theoretical bases and describes the human genome, as well as simple and complex genes transmission. It also deals with the essentials of population genetics and focuses on the issue of genetic defects and medical consequences.
Chapter 1. Genes and genome Chapter 2. Gene transmission Chapter 3. Complex gene transmission Chapter 4. Population genetics Chapter 5. Genetic defects |
 |  | Introduction to Human Anatomy |

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 | Please look at ANAT0110-A-a |
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| Course objective : |
 |  | General biology preparing to biomedical and dental sciences, including introduction to molecular biology |

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 |  | General Embryology |

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 | Session 1:
- The development of gametes: general principles - Oogenesis - Spermatogenesis
Session 2:
- Fertilization - Segmentation
Session 3:
- Didermic embryos and development of placenta and amniotic membranes - Gastrulation - Definition of inducer tissues
Session 4:
- Three-dimensional embryos - Branchiomery - Systems for specific exchanges with the external world: . Birds . Mammals . Multiple gestation
Session 5:
- Cell bases for morphogenesis - Adhesion or environment-analysis molecules - Development genes |
 |  | General Genetics |

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 | - Defining the organization of genes. Defining intragenic and extragenic DNA. Understanding prokaryotic and eukaryotic genomic structures.
- Understanding the rules for the hereditary transmission of simple genetic characters. Understanding genetic recombination mechanisms.
- Understanding the notion of quantitative trait. Assessing interactions between genes and the environment for the determination of complex traits. Understanding methods for exploring the role of heredity in the determination of complex traits and pathologies.
- Understanding how intra- or interpopulation genetic variations can be observed. Mastering and applying the Hardy-Weinberg law. Mastering and understanding how to modify the Hardy-Weinberg balance. |
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| Prerequisites : |
 |  | General biology preparing to biomedical and dental sciences, including introduction to molecular biology |

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 | xx |
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| Workshops : |
 |  | General biology preparing to biomedical and dental sciences, including introduction to molecular biology |

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| Organization : |
 |  | General biology preparing to biomedical and dental sciences, including introduction to molecular biology |

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 |  | General Embryology |

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 | The course is taught in the second term. Schedules and rooms will be published in the vade mecum. |
 |  | General Genetics |

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 | Lecture in French + 1 repetition with exercises 10 hours, 2nd term +1 hour repetition at the end of the term On Fridays from 10:15am to 12:15am. |
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| Written notes : |
 |  | General biology preparing to biomedical and dental sciences, including introduction to molecular biology |

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 | Analyse Génétique Moderne by Griffiths, Gelbart, Miller & Lewontin, De Boeck Université. |
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| Assessment : |
 |  | General biology preparing to biomedical and dental sciences, including introduction to molecular biology |

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 | xx |
 |  | General Embryology |

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 | Written test during the June biomedical sciences module: open questions, true/false questions and multiple-choice questions. |
 |  | General Genetics |

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 | Within the biology module. Written exam (multiple choice + true/false questions with explanations). |
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| Contacts : |
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 | Lecturer in charge
Bours Vincent, Professor CHU B35 Phone: 04-3668145 Email: vbours@ulg.ac.be
Secretary
Fertons Marianne
Phone: 04-3668145 Email: genetique.humaine@ulg.ac.be |
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| Remarks : |
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 | None. |
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