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| EPID0710-1 | Advanced course of Epidemiology, Partim I: Advanced techniques of intervention in epidemiology, partim II: Econometrics applied to epidemiology, partim III: Quantitative methods in evidence-based medicine
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| Duration : | 15h Th, 15h Pr |
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| Credits/ECTS : |
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| Holder(s) : | |
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| Language : | Langue française |
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| Course contents : | Partim I :
Introduction: evidence-based medicine
Drugs development
- Phase I
- Phase II
- Phase III
- Phase IV
Clinical trial methodology
- Characteristics of a protocol
- Particular clinical trial
- Informed consent
- Clinical trial analysis
Approach of medical literature
Partim II :
- Introduction to decision analysis
- Application to therapeutic strategies and diagnostic tests
- Quality of life appraisals
- Cost-effectiveness and cost-benefit analysis
Partim III :
Introduction.
1. Introductory example to EBM
2. Critical appraisal of EBM
3. The weight of evidence in medicine
4. EBM and modern quantitative methods
5. Applications to clinical experimentation in humans
6. Meta-Analysis
7. Publication Bias
8. Applications to the evaluation of a diagnostic or prognostic test |
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| Course objective : | Partim I:
- To acquire basis to perform clinical trial
- To discuss interventional epidemiology with a pultidisciplinary point of view
- To learn to consult international clinical trial directives
Partim II:
To introduce decision analysis and medico-economic models to students preparing a public health degree.
Partim III:
The goal of this class is to provide the student with the elements required for him to critically appraise the medical scientific data he will be confronted with in his future professional activities, and during the realization of his thesis. The lessons will cover the evaluation of the levels of evidence, effect estimates, randomized controlled trials design and analysis, meta-analysis and the development and evaluation of predictive approaches. |
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| Prerequisites : | Basis of epidemiology
(Professeur J.Y. REGINSTER)
Basis of statistics and probability (Professeur A. ALBERT) |
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| Workshops : | Partim I et III: Yes
Partim II: Critical analyses of scientific papers. Practical exercises. |
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| Organization : | 15 theoric hours
15 practical hours |
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| Written notes : | Extensive material will be distributed during the first lesson. |
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| Assessment : | Written exam |
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| Contacts : | Pr. J.Y. REGINSTER, DSSP
Epidemiology, Public Health and Health Economics
CHU Sart Tilman (B23), 4000 Liège.
Phone : +32 4 366 25 01
Fax: +32 4 366 28 12
Email: EPISP@ulg.ac.be
Partim I: O. BRUYERE
Partim II: O. ETHGEN
Partim III: F. RICHY
Phone: +32 4 366 25 81 |
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