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| BIOL0803-1 | Compléments de physiologie moléculaire et cellulaire
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| Duration : | 40h Th |
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| Credits/ECTS : |
| "licencié" biochemical sciences, 2nd year | | | | 5 |
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| Master in Biochemistry, cell and molecule biology, in-depth approach, 1st year | | Toute l'année | | 5 |
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| Master in Biochemistry, cell and molecule biology, didactic approach, 1st year | | Toute l'année | | 5 |
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| Master in Biochemistry, cell and molecule biology, specialized approach, 1st year | | Toute l'année | | 5 |
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| Master in Biological Sciences | | Toute l'année | | 5 |
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| Holder(s) : | Patrick Motte, Francis Sluse |
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| Language : | Langue française |
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| Course contents : | A) Short introduction :-Structure and organization of biological membranes,-Movement of molecules through the membranes : -i. Simple diffusion -ii. Diffusion through channels -iii. Facilitated transport -iv. Active transport -v. Endo-and exocytosis.
B) Neuronal function : -action potential -role of ion channels - role of active transport - voltage- dependent potassium channel ,sodium channel and calcium channel.
C) Synaptic function : -short recall - role of presynaptic voltage-dependent channels - postsynaptic channels -i. ligand-dependent(fast,slow) -ii. voltage-dependent.
D) Sensory receptors : - recall of the steps of signal transduction - mechanoreceptors - chemoreceptors - electroreceptors - thermoreceptors - photoreceptors - role of ionic transports.
E) Mechanisms of secretion : -recall of basal mechanisms - exocrine, endocrine secretions and neurosecretion - membrane receptors : i. channel receptors, ii. catalytic receptors - water flux : aquaporine.
F)Control of muscle contraction : - contraction-relaxation cycle - receptors in triads - calcium channel - calcium ATPase.
G) Intracellular signalling. |
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| Course objective : | Study at the cellular and molecular levels of the main processes in animal physiology. When the molecular structure of a protein responsible of a given process is known, the aim of the teaching will be to link this process with the molecular mechanism of the protein. |
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| Prerequisites : | Physiology, biology |
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| Organization : | 90 min lesson during 1st semester |
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| Written notes : | The powerpoint of every lessons is provided |
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| Assessment : | Le mode d'évaluation sera choisi en concertation avec les étudiants. Pour réussir, il faut une cote totale de 10/20 minimum, et au moins 8/20 auprès de chaque examinateur. |
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| Contacts : | F. SLUSE
Laboratory of Bioénergétics, Institute of Chemistry, Bât. B6c (3ème étage), 4000 Liège 1 (Sart Tilman).
Tél. : 04/366.35.87 ou 35.71 - Fax : 04/366.28.78 - E-mail : F.Sluse@ulg.ac.be |
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