Home - Search by Faculty - By teacher - By course


BIOC0204-1

Biochemistry and thermodynamics of biological systems


Duration :40h Th, 20h Pr
Credits/ECTS :
2nd year of a Bachelor's degree in biological sciences6
Holder(s) :Moreno Galleni
Course contents : - Thermodynamic

Free energy and activation energy

Free energy and oxydoreduction potential

Reversibility of the biochemical reaction

chemical potential

Osmose phenomenon

Introduction to the mechanism of diffusion

- Nature of the non covalent interactions between biomolecules

-Organisation levels of proteins

- Enzymes

Co-enzymes, co-factors and co-substrates

Introduction to enzymatic kinetic

Introduction to allosteric mechanism

Example of catalysis: chymotrypsin and the family of active site serine proteolytic enzymes

- Proteins of interest

Myoglobin and hemoglobin

Immunoglobulins

- Carbohydrates and glycoproteins

- Lipids and lipoproteins

-Introduction to bioenergetics

-Carbohydrate catabolism

Glycogenolysis

Glycolysis and its regulation

Destiny of pyruvate in anaerobic conditions

Destiny of pyruvate in aerobic condition

Oxydative phosphorylation

- Gluconeogenesis and its regulation

destiny of carbohydrates in the organism

-Degradation of fatty acids and lipids

-Protein degradation and destiny of amino acids

- Biochimistry of the gene - DNA

DNA composition

Structure of DNA

Gentic information and DNA

DNA organisation in chromosomes

- Dynamic of genes

DNA replication in prokaryotes

DNA replication in eukaryotes

Genetic code

Transcription and messager RNA

- Protein biosynthesis

Transfer RNA or tRNA

Ribosomes

mechanism of protein synthesis

Destiny of proteins

-Control of gentic expression
Course objective : The lectures will be devoted on :

- physical and chemical basis of biochemistry

- molecular basis of metabolic pathways involved in the regulation of biological process
Prerequisites : Basic lecture in inorganic and organic chemistry

Courses of general biology
Workshops : 3 lectures

- kinetic

- Determination od protein concentration

- Dyalisis and molecular sieve

Place: Batiment de chimie (B6 - sart Tilman) pour des travaux pratiques de candidature
Organization : 20 lecture of 2 hours

3 laboratory sessions

1 exercice session
Written notes : Overheads and Power Point presentation

Syllabus
Assessment : Written and oral examination
Contacts : Lectures:
Galleni Moreno, Local 3/7, Institut de Chimie , B6. Sart Tilman
Tel:04/3663549 - Fax:04/3663364 - Email:mgalleni@ulg.ac.be

Practical lectures:

Dr. Feller Georges, Chef de Travaux
Institut de chimie B6 Sart Tilman
Tel 04/3663343 Fax 04/3663364 email:gfeller@ulg.ac.be

Berlemont Renaud, Assistant
local 1/34, institut de Chimie, B6a. Sart Tilman
Tel: 04/3663348- Fax: 04/3663396 - Email:rberlemont@student.ulg.ac.be




ULg : Students and Studies Administration - Academic Affairs
Contact : Monique Marcourt, direction A.E.E.
Date of data : 18/05/2007
Developed by SEGI